↓ Skip to main content

Copaiba oil-resin (Copaifera reticulata Ducke) modulates the inflammation in a model of injury to rats’ tongues

Overview of attention for article published in BMC Complementary and Alternative Medicine, June 2017
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)

Mentioned by

twitter
5 tweeters
facebook
1 Facebook page
video
1 video uploader

Citations

dimensions_citation
17 Dimensions

Readers on

mendeley
72 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Copaiba oil-resin (Copaifera reticulata Ducke) modulates the inflammation in a model of injury to rats’ tongues
Published in
BMC Complementary and Alternative Medicine, June 2017
DOI 10.1186/s12906-017-1820-2
Pubmed ID
Authors

Francisco Bruno Teixeira, Raíra de Brito Silva, Osmar Alves Lameira, Liana Preto Webber, Roberta Souza D’Almeida Couto, Manoela Domingues Martins, Rafael Rodrigues Lima

Abstract

The regeneration of integrity and tissue homeostasis after injury is a fundamental property and involves complex biological processes fully dynamic and interconnected. Although there are medications prescribed to accelerate the process of wound healing by reducing the exaggerated inflammatory response, comes the need to search for different compounds of Amazonian biodiversity that can contribute to the acceleration of the healing process. Among these products, the copaiba oil-resin is one of the most prominent feature in this scenario, as they have been reported its medicinal properties. Aiming to evaluate the anti-inflammatory and healing effect of copaiba oil-resin (Copaifera reticulata Ducke) in transfixing injury of rats' tongues first proceeded up the copaiba oil-resin oral toxicity test in 5 male mice to stipulate the therapeutic dose which was established at 200 mg/kg/day. Then it was induced transfixing injury in a total of 15 Wistar rats. The animals were randomly divided into three groups based on the treatment: control group, dexamethasone group and copaiba oil-resin group. After 7 days of treatment, histological slides stained with hematoxylin and eosin was prepared. Immunohistochemistry for CD68 (macrophage marker) was performed and analyzed by the cell counter Image J. The acute toxicity test showed that the oil-resin copal has low toxicity. Furthermore, copaiba oil-resin therapy modulates the inflammatory response by decreasing the chronic inflammatory infiltrate, edema and specifically the number of macrophages. The results indicate the potential of the Amazon region and showed up relevant because therapy with this extract modulates the inflammatory process.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 72 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 15 21%
Student > Bachelor 11 15%
Student > Ph. D. Student 10 14%
Researcher 8 11%
Student > Postgraduate 4 6%
Other 7 10%
Unknown 17 24%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 14 19%
Medicine and Dentistry 13 18%
Agricultural and Biological Sciences 6 8%
Biochemistry, Genetics and Molecular Biology 4 6%
Unspecified 3 4%
Other 10 14%
Unknown 22 31%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 January 2019.
All research outputs
#5,732,749
of 21,778,818 outputs
Outputs from BMC Complementary and Alternative Medicine
#839
of 3,016 outputs
Outputs of similar age
#86,964
of 289,238 outputs
Outputs of similar age from BMC Complementary and Alternative Medicine
#1
of 3 outputs
Altmetric has tracked 21,778,818 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 3,016 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.7. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,238 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them