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Copaiba oil-resin (Copaifera reticulata Ducke) modulates the inflammation in a model of injury to rats’ tongues

Overview of attention for article published in BMC Complementary Medicine and Therapies, June 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

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5 X users
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1 patent
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1 Facebook page
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1 YouTube creator

Citations

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22 Dimensions

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85 Mendeley
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Title
Copaiba oil-resin (Copaifera reticulata Ducke) modulates the inflammation in a model of injury to rats’ tongues
Published in
BMC Complementary Medicine and Therapies, June 2017
DOI 10.1186/s12906-017-1820-2
Pubmed ID
Authors

Francisco Bruno Teixeira, Raíra de Brito Silva, Osmar Alves Lameira, Liana Preto Webber, Roberta Souza D’Almeida Couto, Manoela Domingues Martins, Rafael Rodrigues Lima

Abstract

The regeneration of integrity and tissue homeostasis after injury is a fundamental property and involves complex biological processes fully dynamic and interconnected. Although there are medications prescribed to accelerate the process of wound healing by reducing the exaggerated inflammatory response, comes the need to search for different compounds of Amazonian biodiversity that can contribute to the acceleration of the healing process. Among these products, the copaiba oil-resin is one of the most prominent feature in this scenario, as they have been reported its medicinal properties. Aiming to evaluate the anti-inflammatory and healing effect of copaiba oil-resin (Copaifera reticulata Ducke) in transfixing injury of rats' tongues first proceeded up the copaiba oil-resin oral toxicity test in 5 male mice to stipulate the therapeutic dose which was established at 200 mg/kg/day. Then it was induced transfixing injury in a total of 15 Wistar rats. The animals were randomly divided into three groups based on the treatment: control group, dexamethasone group and copaiba oil-resin group. After 7 days of treatment, histological slides stained with hematoxylin and eosin was prepared. Immunohistochemistry for CD68 (macrophage marker) was performed and analyzed by the cell counter Image J. The acute toxicity test showed that the oil-resin copal has low toxicity. Furthermore, copaiba oil-resin therapy modulates the inflammatory response by decreasing the chronic inflammatory infiltrate, edema and specifically the number of macrophages. The results indicate the potential of the Amazon region and showed up relevant because therapy with this extract modulates the inflammatory process.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 85 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 18 21%
Student > Bachelor 12 14%
Student > Ph. D. Student 12 14%
Researcher 6 7%
Student > Postgraduate 5 6%
Other 9 11%
Unknown 23 27%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 17 20%
Medicine and Dentistry 15 18%
Biochemistry, Genetics and Molecular Biology 6 7%
Agricultural and Biological Sciences 6 7%
Chemistry 3 4%
Other 10 12%
Unknown 28 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 May 2023.
All research outputs
#4,301,826
of 24,257,963 outputs
Outputs from BMC Complementary Medicine and Therapies
#794
of 3,811 outputs
Outputs of similar age
#72,078
of 321,092 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#20
of 125 outputs
Altmetric has tracked 24,257,963 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,811 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.1. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,092 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 125 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.