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Mendeley readers
Attention Score in Context
| Title |
Cytochrome P450 2E1 (CYP2E1) regulates the response to oxidative stress and migration of breast cancer cells
|
|---|---|
| Published in |
Breast Cancer Research, November 2013
|
| DOI | 10.1186/bcr3574 |
| Pubmed ID | |
| Authors |
Travis Leung, Ramkumar Rajendran, Subir Singh, Richa Garva, Marija Krstic-Demonacos, Constantinos Demonacos |
| Abstract |
The cytochrome P450 (CYP) enzymes are a class of heme-containing enzymes involved in phase I metabolism of a large number of xenobiotics. The CYP family member CYP2E1 metabolises many xenobiotics and pro-carcinogens, it is not just expressed in the liver but also in many other tissues such as the kidney, the lung, the brain, the gastrointestinal tract and the breast tissue. It is induced in several pathological conditions including cancer, obesity, and type II diabetes implying that this enzyme is implicated in other biological processes beyond its role in phase I metabolism. Despite the detailed description of the role of CYP2E1 in the liver, its functions in other tissues have not been extensively studied. In this study, we investigated the functional significance of CYP2E1 in breast carcinogenesis. |
Mendeley readers
The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 1% |
| Belgium | 1 | 1% |
| Australia | 1 | 1% |
| Unknown | 91 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 16 | 17% |
| Student > Ph. D. Student | 12 | 13% |
| Researcher | 12 | 13% |
| Student > Master | 11 | 12% |
| Student > Doctoral Student | 9 | 10% |
| Other | 16 | 17% |
| Unknown | 18 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 21 | 22% |
| Agricultural and Biological Sciences | 19 | 20% |
| Medicine and Dentistry | 11 | 12% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 7% |
| Chemistry | 6 | 6% |
| Other | 8 | 9% |
| Unknown | 22 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 February 2014.
All research outputs
#2,329,592
of 25,371,288 outputs
Outputs from Breast Cancer Research
#225
of 2,052 outputs
Outputs of similar age
#21,549
of 229,108 outputs
Outputs of similar age from Breast Cancer Research
#8
of 36 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 229,108 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.