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Antimicrobial susceptibility pattern of Shigella spp. isolated from children under 5 years of age attending tertiary care hospitals, Nepal along with first finding of ESBL-production

Overview of attention for article published in BMC Research Notes, June 2017
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Title
Antimicrobial susceptibility pattern of Shigella spp. isolated from children under 5 years of age attending tertiary care hospitals, Nepal along with first finding of ESBL-production
Published in
BMC Research Notes, June 2017
DOI 10.1186/s13104-017-2512-1
Pubmed ID
Authors

Subhash Dhital, Jeevan Bahadur Sherchand, Bharat Mani Pokharel, Keshab Parajuli, Shyam Kumar Mishra, Sangita Sharma, Hari Prasad Kattel, Sundar Khadka, Sulochana Khatiwada, Basista Rijal

Abstract

Shigella is an important cause of bacterial gastroenteritis in resource-poor countries. The treatment of shigellosis mostly requires antibiotics. However, the increase of multidrug resistance along with emergence of extended-spectrum β-lactamase and ciprofloxacin resistance among Shigella spp. has challenged the situation. This study was conducted to determine the distribution of species and antibiotic susceptibility pattern of Shigella species isolated from stool specimen among children less than 5 years of age in Nepal. Out of total 717 stool samples collected, 15 cases of Shigella spp. was isolated which includes 12 S. flexneri and 3 S. sonnei. Multidrug resistance was found among 13(86%) of the isolates. One of the isolates of S. flexneri was found to be ESBL-producer with MIC >256 mg/L for cefixime. The high occurrence of multidrug resistance among Shigella spp. along with a case of ESBL-production for the first time in Nepal alarms the concerns about dissemination of the resistant isolates. So, systemic monitoring of the antimicrobial susceptibility pattern of Shigella spp. is becoming crucial to guide therapy.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 49 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 20%
Student > Ph. D. Student 7 14%
Student > Master 5 10%
Student > Doctoral Student 4 8%
Lecturer > Senior Lecturer 4 8%
Other 6 12%
Unknown 13 27%
Readers by discipline Count As %
Medicine and Dentistry 11 22%
Immunology and Microbiology 6 12%
Biochemistry, Genetics and Molecular Biology 5 10%
Nursing and Health Professions 4 8%
Agricultural and Biological Sciences 3 6%
Other 6 12%
Unknown 14 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 June 2017.
All research outputs
#20,428,633
of 22,981,247 outputs
Outputs from BMC Research Notes
#3,579
of 4,283 outputs
Outputs of similar age
#275,988
of 317,201 outputs
Outputs of similar age from BMC Research Notes
#69
of 81 outputs
Altmetric has tracked 22,981,247 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,283 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,201 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 81 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.