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Role of mesenchymal stem cells, their derived factors, and extracellular vesicles in liver failure

Overview of attention for article published in Stem Cell Research & Therapy, June 2017
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (63rd percentile)
  • Good Attention Score compared to outputs of the same age and source (73rd percentile)

Mentioned by

twitter
5 tweeters

Citations

dimensions_citation
32 Dimensions

Readers on

mendeley
60 Mendeley
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Title
Role of mesenchymal stem cells, their derived factors, and extracellular vesicles in liver failure
Published in
Stem Cell Research & Therapy, June 2017
DOI 10.1186/s13287-017-0576-4
Pubmed ID
Authors

Jie Wang, Panpan Cen, Jiajia Chen, Linxiao Fan, Jun Li, Hongcui Cao, Lanjuan Li

Abstract

Liver failure is a severe clinical syndrome with a poor prognosis. Mesenchymal stem cell (MSC) transplantation has emerged as a new intervention in treating liver failure. It is conventionally recognized that MSCs exert their therapeutic effect mainly through transdifferentiation. Recently, published articles have shown that MSCs work in liver failure by secreting trophic and immunomodulatory factors as well as extracellular vesicles (EVs) before transdifferentiation. In particular,MSC-derived EVs have shown similar curative effects as MSCs. Here we review the role of MSCs as well as their derived factors and EVs in liver failure and discuss the use of MSC-derived EVs instead of intact MSCs in treating liver failure.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 60 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 17%
Student > Master 8 13%
Student > Bachelor 7 12%
Student > Postgraduate 6 10%
Student > Doctoral Student 5 8%
Other 14 23%
Unknown 10 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 20 33%
Medicine and Dentistry 13 22%
Agricultural and Biological Sciences 5 8%
Immunology and Microbiology 2 3%
Nursing and Health Professions 1 2%
Other 6 10%
Unknown 13 22%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 June 2017.
All research outputs
#3,169,323
of 11,383,682 outputs
Outputs from Stem Cell Research & Therapy
#300
of 907 outputs
Outputs of similar age
#91,740
of 264,609 outputs
Outputs of similar age from Stem Cell Research & Therapy
#12
of 45 outputs
Altmetric has tracked 11,383,682 research outputs across all sources so far. This one is in the 49th percentile – i.e., 49% of other outputs scored the same or lower than it.
So far Altmetric has tracked 907 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,609 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.
We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.