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Role of mesenchymal stem cells, their derived factors, and extracellular vesicles in liver failure

Overview of attention for article published in Stem Cell Research & Therapy, June 2017
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (54th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

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5 X users

Citations

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42 Dimensions

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64 Mendeley
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Title
Role of mesenchymal stem cells, their derived factors, and extracellular vesicles in liver failure
Published in
Stem Cell Research & Therapy, June 2017
DOI 10.1186/s13287-017-0576-4
Pubmed ID
Authors

Jie Wang, Panpan Cen, Jiajia Chen, Linxiao Fan, Jun Li, Hongcui Cao, Lanjuan Li

Abstract

Liver failure is a severe clinical syndrome with a poor prognosis. Mesenchymal stem cell (MSC) transplantation has emerged as a new intervention in treating liver failure. It is conventionally recognized that MSCs exert their therapeutic effect mainly through transdifferentiation. Recently, published articles have shown that MSCs work in liver failure by secreting trophic and immunomodulatory factors as well as extracellular vesicles (EVs) before transdifferentiation. In particular,MSC-derived EVs have shown similar curative effects as MSCs. Here we review the role of MSCs as well as their derived factors and EVs in liver failure and discuss the use of MSC-derived EVs instead of intact MSCs in treating liver failure.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 64 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 16%
Student > Master 9 14%
Student > Postgraduate 6 9%
Student > Bachelor 6 9%
Student > Doctoral Student 5 8%
Other 14 22%
Unknown 14 22%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 19 30%
Medicine and Dentistry 13 20%
Agricultural and Biological Sciences 5 8%
Immunology and Microbiology 2 3%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 6 9%
Unknown 17 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 June 2017.
All research outputs
#7,531,527
of 22,981,247 outputs
Outputs from Stem Cell Research & Therapy
#759
of 2,428 outputs
Outputs of similar age
#120,845
of 317,266 outputs
Outputs of similar age from Stem Cell Research & Therapy
#20
of 62 outputs
Altmetric has tracked 22,981,247 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,428 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,266 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.