Title |
Segmentation of epidermal tissue with histopathological damage in images of haematoxylin and eosin stained human skin
|
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Published in |
BMC Medical Imaging, February 2014
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DOI | 10.1186/1471-2342-14-7 |
Pubmed ID | |
Authors |
Juliana M Haggerty, Xiao N Wang, Anne Dickinson, Chris J O’Malley, Elaine B Martin |
Abstract |
Digital image analysis has the potential to address issues surrounding traditional histological techniques including a lack of objectivity and high variability, through the application of quantitative analysis. A key initial step in image analysis is the identification of regions of interest. A widely applied methodology is that of segmentation. This paper proposes the application of image analysis techniques to segment skin tissue with varying degrees of histopathological damage. The segmentation of human tissue is challenging as a consequence of the complexity of the tissue structures and inconsistencies in tissue preparation, hence there is a need for a new robust method with the capability to handle the additional challenges materialising from histopathological damage. |
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