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Mendeley readers
| Title |
Human adipose-derived stem cell transplantation as a potential therapy for collagen VI-related congenital muscular dystrophy
|
|---|---|
| Published in |
Stem Cell Research & Therapy, February 2014
|
| DOI | 10.1186/scrt411 |
| Pubmed ID | |
| Authors |
Vitali Alexeev, Machiko Arita, Adele Donahue, Paolo Bonaldo, Mon-Li Chu, Olga Igoucheva |
| Abstract |
Congenital muscular dystrophies (CMD) are a clinically and genetically heterogeneous group of neuromuscular disorders characterized by muscle weakness within the first two years of life. Collagen VI-related muscle disorders have recently emerged as one of the most common types of CMD. COL6 CMD is caused by deficiency and/or dysfunction of extracellular matrix (ECM) protein collagen VI. Currently, there is no specific treatment for this disabling and life-threatening disease. The primary cellular targets for collagen VI CMD therapy are fibroblasts in muscle, tendon and skin, as opposed to muscle cells for other types of muscular dystrophies. However, recent advances in stem cell research have raised the possibility that use of adult stem cells may provide dramatic new therapies for treatment of COL6 CMD. |
Mendeley readers
The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 2 | 3% |
| United States | 1 | 2% |
| Italy | 1 | 2% |
| Brazil | 1 | 2% |
| Unknown | 61 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 14 | 21% |
| Student > Ph. D. Student | 13 | 20% |
| Student > Bachelor | 10 | 15% |
| Student > Master | 5 | 8% |
| Unspecified | 4 | 6% |
| Other | 12 | 18% |
| Unknown | 8 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 17 | 26% |
| Medicine and Dentistry | 12 | 18% |
| Biochemistry, Genetics and Molecular Biology | 9 | 14% |
| Unspecified | 4 | 6% |
| Engineering | 4 | 6% |
| Other | 10 | 15% |
| Unknown | 10 | 15% |