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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genetic–epigenetic interactions in cis: a major focus in the post-GWAS era
|
|---|---|
| Published in |
Genome Biology, June 2017
|
| DOI | 10.1186/s13059-017-1250-y |
| Pubmed ID | |
| Authors |
Catherine Do, Alyssa Shearer, Masako Suzuki, Mary Beth Terry, Joel Gelernter, John M. Greally, Benjamin Tycko |
| Abstract |
Studies on genetic-epigenetic interactions, including the mapping of methylation quantitative trait loci (mQTLs) and haplotype-dependent allele-specific DNA methylation (hap-ASM), have become a major focus in the post-genome-wide-association-study (GWAS) era. Such maps can nominate regulatory sequence variants that underlie GWAS signals for common diseases, ranging from neuropsychiatric disorders to cancers. Conversely, mQTLs need to be filtered out when searching for non-genetic effects in epigenome-wide association studies (EWAS). Sequence variants in CCCTC-binding factor (CTCF) and transcription factor binding sites have been mechanistically linked to mQTLs and hap-ASM. Identifying these sites can point to disease-associated transcriptional pathways, with implications for targeted treatment and prevention. |
X Demographics
The data shown below were collected from the profiles of 31 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 8 | 26% |
| United States | 6 | 19% |
| Mexico | 1 | 3% |
| Tunisia | 1 | 3% |
| Japan | 1 | 3% |
| France | 1 | 3% |
| Canada | 1 | 3% |
| Unknown | 12 | 39% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 15 | 48% |
| Scientists | 12 | 39% |
| Science communicators (journalists, bloggers, editors) | 4 | 13% |
Mendeley readers
The data shown below were compiled from readership statistics for 242 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | <1% |
| Unknown | 240 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 57 | 24% |
| Student > Ph. D. Student | 53 | 22% |
| Student > Master | 26 | 11% |
| Student > Bachelor | 15 | 6% |
| Student > Doctoral Student | 11 | 5% |
| Other | 39 | 16% |
| Unknown | 41 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 70 | 29% |
| Agricultural and Biological Sciences | 70 | 29% |
| Medicine and Dentistry | 14 | 6% |
| Neuroscience | 7 | 3% |
| Computer Science | 5 | 2% |
| Other | 21 | 9% |
| Unknown | 55 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 April 2018.
All research outputs
#1,966,144
of 25,382,440 outputs
Outputs from Genome Biology
#1,651
of 4,468 outputs
Outputs of similar age
#37,613
of 329,774 outputs
Outputs of similar age from Genome Biology
#33
of 64 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,468 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,774 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 64 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.