Title |
Optimal timing of renal replacement therapy initiation in acute kidney injury: the elephant felt by the blindmen?
|
---|---|
Published in |
Critical Care, June 2017
|
DOI | 10.1186/s13054-017-1713-2 |
Pubmed ID | |
Authors |
Chih-Chung Shiao, Tao-Min Huang, Herbert D. Spapen, Patrick M. Honore, Vin-Cent Wu |
Abstract |
Renal replacement therapy (RRT) is a key component in the management of severe acute kidney injury (AKI) in critically ill patients. Many cohort studies, meta-analyses, and two recent large randomized prospective trials which evaluated the relationship between the timing of RRT initiation and patient outcome remain inconclusive due to substantial differences in study design, patient population, AKI definition, and RRT indication. A cause-specific diagnosis of AKI based on current staging criteria plus a sensitive biomarker (panel) that allows creating a homogeneous study population is definitely needed to assess the impact of early versus late initiation of RRT on patient outcome. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 2 | 5% |
United Kingdom | 2 | 5% |
India | 2 | 5% |
Spain | 2 | 5% |
Mexico | 2 | 5% |
Ireland | 1 | 3% |
Venezuela, Bolivarian Republic of | 1 | 3% |
Dominican Republic | 1 | 3% |
France | 1 | 3% |
Other | 5 | 14% |
Unknown | 18 | 49% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 21 | 57% |
Practitioners (doctors, other healthcare professionals) | 11 | 30% |
Science communicators (journalists, bloggers, editors) | 3 | 8% |
Scientists | 2 | 5% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 61 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 10 | 16% |
Researcher | 6 | 10% |
Student > Master | 5 | 8% |
Student > Doctoral Student | 4 | 7% |
Student > Bachelor | 4 | 7% |
Other | 12 | 20% |
Unknown | 20 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 33 | 54% |
Nursing and Health Professions | 3 | 5% |
Social Sciences | 2 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Chemistry | 1 | 2% |
Other | 0 | 0% |
Unknown | 21 | 34% |