Title |
Fluorophotometry as a diagnostic tool for the evaluation of dry eye disease
|
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Published in |
BMC Ophthalmology, May 2006
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DOI | 10.1186/1471-2415-6-20 |
Pubmed ID | |
Authors |
Magid M Fahim, Shamim Haji, Chakravarthy V Koonapareddy, Vincent C Fan, Penny A Asbell |
Abstract |
Dry eye disease is a common debilitating ocular disease. Current diagnostic tests used in dry eye disease are often neither sensitive nor reproducible, making it difficult to accurately diagnose and determine end points for clinical trials, or evaluate the usefulness of different medications in the treatment of dry eye disease. The recently developed fluorophotometer can objectively detect changes in the corneal epithelium by quantitatively measuring its barrier function or permeability. The purpose of the study is to investigate the use of corneal fluorescein penetration measured by the fluorophotometer as a diagnostic tool in the evaluation of dry eye patients. |
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