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Harnessing RNAi nanomedicine for precision therapy

Overview of attention for article published in Molecular and Cellular Therapies, February 2014
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Mentioned by

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4 X users
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1 Facebook page

Citations

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22 Dimensions

Readers on

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54 Mendeley
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Title
Harnessing RNAi nanomedicine for precision therapy
Published in
Molecular and Cellular Therapies, February 2014
DOI 10.1186/2052-8426-2-5
Pubmed ID
Authors

Dan Peer

Abstract

Utilizing RNA interference as an innovative therapeutic strategy has an immense likelihood to generate novel concepts in precision medicine. Several clinical trials are on the way with some positive initial results. Yet, targeting of RNAi payloads such as small interfering RNAs (siRNAs), microRNA (miR) mimetic or anti-miR (antagomirs) into specific cell types remains a challenge. Major attempts are done for developing nano-sized carriers that could overcome systemic, local and cellular barriers. This progress report will focus on the recent advances in the RNAi world, detailing strategies of systemic passive tissue targeting and active cellular targeting, which is often considered as the holy grail of drug delivery.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 54 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 22%
Student > Ph. D. Student 10 19%
Student > Master 8 15%
Student > Bachelor 6 11%
Student > Doctoral Student 5 9%
Other 5 9%
Unknown 8 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 24%
Chemistry 7 13%
Biochemistry, Genetics and Molecular Biology 6 11%
Medicine and Dentistry 5 9%
Pharmacology, Toxicology and Pharmaceutical Science 3 6%
Other 11 20%
Unknown 9 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 February 2015.
All research outputs
#15,228,078
of 25,457,858 outputs
Outputs from Molecular and Cellular Therapies
#23
of 36 outputs
Outputs of similar age
#176,707
of 323,018 outputs
Outputs of similar age from Molecular and Cellular Therapies
#3
of 5 outputs
Altmetric has tracked 25,457,858 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 36 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one scored the same or higher as 13 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,018 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.