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Mendeley readers
Attention Score in Context
| Title |
Adeno-associated viral serotypes produce differing titers and differentially transduce neurons within the rat basal and lateral amygdala
|
|---|---|
| Published in |
BMC Neuroscience, February 2014
|
| DOI | 10.1186/1471-2202-15-28 |
| Pubmed ID | |
| Authors |
Roopashri Holehonnur, Jonathan A Luong, Dushyant Chaturvedi, Anthony Ho, Srihari K Lella, Matthew P Hosek, Jonathan E Ploski |
| Abstract |
In recent years, there has been an increased interest in using recombinant adeno-associated viruses (AAV) to make localized genetic manipulations within the rodent brain. Differing serotypes of AAV possess divergent capsid protein sequences and these variations greatly influence each serotype's ability to transduce particular cell types and brain regions. We therefore aimed to determine the AAV serotype that is optimal for targeting neurons within the Basal and Lateral Amygdala (BLA) since the transduction efficiency of AAV has not been previously examined within the BLA. This region is desirable to genetically manipulate due to its role in emotion, learning & memory, and numerous psychiatric disorders. We accomplished this by screening 9 different AAV serotypes (AAV2/1, AAV2/2, AAV2/5, AAV2/7, AAV2/8, AAV2/9, AAV2/rh10, AAV2/DJ and AAV2/DJ8) designed to express red fluorescent protein (RFP) under the regulation of an alpha Ca2+/calmodulin-dependent protein kinase II promoter (αCaMKII). |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 147 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Unknown | 145 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 44 | 30% |
| Student > Ph. D. Student | 28 | 19% |
| Student > Master | 14 | 10% |
| Student > Bachelor | 10 | 7% |
| Student > Doctoral Student | 6 | 4% |
| Other | 17 | 12% |
| Unknown | 28 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 48 | 33% |
| Agricultural and Biological Sciences | 41 | 28% |
| Biochemistry, Genetics and Molecular Biology | 14 | 10% |
| Medicine and Dentistry | 7 | 5% |
| Psychology | 4 | 3% |
| Other | 5 | 3% |
| Unknown | 28 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 January 2024.
All research outputs
#4,791,077
of 25,263,619 outputs
Outputs from BMC Neuroscience
#204
of 1,290 outputs
Outputs of similar age
#44,130
of 231,529 outputs
Outputs of similar age from BMC Neuroscience
#4
of 36 outputs
Altmetric has tracked 25,263,619 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,290 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 231,529 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.