Title |
Role of adult neurogenesis in hippocampal-cortical memory consolidation
|
---|---|
Published in |
Molecular Brain, February 2014
|
DOI | 10.1186/1756-6606-7-13 |
Pubmed ID | |
Authors |
Takashi Kitamura, Kaoru Inokuchi |
Abstract |
Acquired memory is initially dependent on the hippocampus (HPC) for permanent memory formation. This hippocampal dependency of memory recall progressively decays with time, a process that is associated with a gradual increase in dependency upon cortical structures. This process is commonly referred to as systems consolidation theory. In this paper, we first review how memory becomes hippocampal dependent to cortical dependent with an emphasis on the interactions that occur between the HPC and cortex during systems consolidation. We also review the mechanisms underlying the gradual decay of HPC dependency during systems consolidation from the perspective of memory erasures by adult hippocampal neurogenesis. Finally, we discuss the relationship between systems consolidation and memory precision. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Science communicators (journalists, bloggers, editors) | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 2% |
France | 2 | <1% |
Germany | 1 | <1% |
United Kingdom | 1 | <1% |
Poland | 1 | <1% |
Unknown | 201 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 46 | 22% |
Student > Bachelor | 35 | 17% |
Student > Master | 31 | 15% |
Researcher | 21 | 10% |
Student > Doctoral Student | 16 | 8% |
Other | 37 | 18% |
Unknown | 24 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 57 | 27% |
Neuroscience | 55 | 26% |
Psychology | 25 | 12% |
Medicine and Dentistry | 19 | 9% |
Biochemistry, Genetics and Molecular Biology | 10 | 5% |
Other | 14 | 7% |
Unknown | 30 | 14% |