Title |
Shorter daily dwelling time in peritoneal dialysis attenuates the epithelial-to-mesenchymal transition of mesothelial cells
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Published in |
BMC Nephrology, February 2014
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DOI | 10.1186/1471-2369-15-35 |
Pubmed ID | |
Authors |
Yi-Che Lee, Yau-Sheng Tsai, Shih-Yuan Hung, Tsun-Mei Lin, Sheng-Hsiang Lin, Hung-Hsiang Liou, Hsiang-Chun Liu, Min-Yu Chang, Hsi-Hao Wang, Li-Chun Ho, Yi-Ting Chen, Hsin-Pao Chen, Hong-Arh Fan, Kuang-Wen Liu, Yung-Tang Kung, Hao-Kuang Wang, Yuan-Yow Chiou |
Abstract |
Peritoneal dialysis (PD) therapy is known to induce morphological and functional changes in the peritoneal membrane. Long-term exposure to conventional bio-incompatible dialysate and peritonitis is the main etiology of inflammation. Consequently, the peritoneal membrane undergoes structural changes, including angiogenesis, fibrosis, and hyalinizing vasculopathy, which ultimately results in technique failure. The epithelial-to-mesenchymal transition (EMT) of mesothelial cells (MCs) plays an important role during the above process; however, the clinical parameters associated with the EMT process of MCs remain to be explored. |
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Unknown | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 28 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 5 | 18% |
Other | 3 | 11% |
Student > Bachelor | 3 | 11% |
Researcher | 3 | 11% |
Professor | 2 | 7% |
Other | 7 | 25% |
Unknown | 5 | 18% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 6 | 21% |
Medicine and Dentistry | 6 | 21% |
Engineering | 3 | 11% |
Nursing and Health Professions | 2 | 7% |
Immunology and Microbiology | 1 | 4% |
Other | 5 | 18% |
Unknown | 5 | 18% |