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Multifaceted interventions for improving spontaneous reporting of adverse drug reactions in a general hospital in China

Overview of attention for article published in BMC Pharmacology and Toxicology, June 2017
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Title
Multifaceted interventions for improving spontaneous reporting of adverse drug reactions in a general hospital in China
Published in
BMC Pharmacology and Toxicology, June 2017
DOI 10.1186/s40360-017-0159-0
Pubmed ID
Authors

Huan Fang, Xiaowen Lin, Jun Zhang, Zhen Hong, Kenji Sugiyama, Takao Nozaki, Tetsuro Sameshima, Susumu Kobayashi, Hiroki Namba, Tetsuya Asakawa

Abstract

The present study investigates changes in spontaneous reporting (SR) compliance and ADR patterns following adoption of a new hospital SR system, and multiple interventions designed for its improvement use under modified drug administration guidelines. In total, 1389 ADR cases were reviewed. Cases were divided into two groups, cases from period 1 (n = 557, from January 2006 to June 2011) under the old SR system and cases in period 2 (n = 832, from July 2011 to December 2016) under the new SR system with multiple interventions to improve physician SR compliance. General information, drug information, and clinical manifestations were investigated and compared between periods. Interventions for improved clinician training, education on knowledge, attitudes, and practices (KAP), and economic incentives substantially improved SR adherence. We also found that changing drug usage patterns (based on the new drug administration guidelines) greatly influenced ADR occurrence and type. We found the SR compliance can be improved by multifaceted interventions. Drug usage patterns also influence ADR occurrence, so programs tailored for rational use are essential. These results could lead to further improvements in the SR system for ADRs in China, and provide guidance for establishing better methods of pharmacovigilance.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 39 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 13 33%
Student > Postgraduate 4 10%
Other 3 8%
Lecturer 2 5%
Researcher 2 5%
Other 5 13%
Unknown 10 26%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 9 23%
Medicine and Dentistry 7 18%
Nursing and Health Professions 3 8%
Social Sciences 2 5%
Psychology 2 5%
Other 4 10%
Unknown 12 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 September 2017.
All research outputs
#18,616,159
of 23,881,329 outputs
Outputs from BMC Pharmacology and Toxicology
#294
of 450 outputs
Outputs of similar age
#230,022
of 317,400 outputs
Outputs of similar age from BMC Pharmacology and Toxicology
#12
of 19 outputs
Altmetric has tracked 23,881,329 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 450 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,400 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.