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Differences in virulence of pneumolysin and autolysin mutants constructed by insertion duplication mutagenesis and in-frame deletion in Streptococcus pneumoniae

Overview of attention for article published in BMC Biotechnology, February 2014
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Title
Differences in virulence of pneumolysin and autolysin mutants constructed by insertion duplication mutagenesis and in-frame deletion in Streptococcus pneumoniae
Published in
BMC Biotechnology, February 2014
DOI 10.1186/1472-6750-14-16
Pubmed ID
Authors

Esther Yip-Mei Liu, Feng-Yee Chang, Jen-Chang Chang, Chang-Phone Fung

Abstract

Insertion duplication mutagenesis (IDM) and in-frame deletion (IFD) are common techniques for studying gene function, and have been applied to pneumolysin (ply), a virulence gene in Streptococcus pneumoniae (D39). Discrepancies in virulence between the two techniques were observed in both the previous and present studies. This phenomenon was also observed during mutation analysis of autolysin (lytA).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 5%
Unknown 18 95%

Demographic breakdown

Readers by professional status Count As %
Other 4 21%
Student > Ph. D. Student 4 21%
Researcher 3 16%
Student > Bachelor 3 16%
Student > Doctoral Student 1 5%
Other 0 0%
Unknown 4 21%
Readers by discipline Count As %
Immunology and Microbiology 4 21%
Agricultural and Biological Sciences 4 21%
Biochemistry, Genetics and Molecular Biology 2 11%
Arts and Humanities 1 5%
Veterinary Science and Veterinary Medicine 1 5%
Other 3 16%
Unknown 4 21%