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X Demographics
Mendeley readers
Attention Score in Context
| Title |
NicE-seq: high resolution open chromatin profiling
|
|---|---|
| Published in |
Genome Biology, June 2017
|
| DOI | 10.1186/s13059-017-1247-6 |
| Pubmed ID | |
| Authors |
V. K. Chaithanya Ponnaluri, Guoqiang Zhang, Pierre-Olivier Estève, George Spracklin, Stephanie Sian, Shuang-yong Xu, Touati Benoukraf, Sriharsa Pradhan |
| Abstract |
Open chromatin profiling integrates information across diverse regulatory elements to reveal the transcriptionally active genome. Tn5 transposase and DNase I sequencing-based methods prefer native or high cell numbers. Here, we describe NicE-seq (nicking enzyme assisted sequencing) for high-resolution open chromatin profiling on both native and formaldehyde-fixed cells. NicE-seq captures and reveals open chromatin sites (OCSs) and transcription factor occupancy at single nucleotide resolution, coincident with DNase hypersensitive and ATAC-seq sites at a low sequencing burden. OCSs correlate with RNA polymerase II occupancy and active chromatin marks, while displaying a contrasting pattern to CpG methylation. Decitabine-mediated hypomethylation of HCT116 displays higher numbers of OCSs. |
X Demographics
The data shown below were collected from the profiles of 73 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 19 | 26% |
| United Kingdom | 13 | 18% |
| Australia | 4 | 5% |
| India | 3 | 4% |
| Germany | 2 | 3% |
| France | 2 | 3% |
| Denmark | 2 | 3% |
| Canada | 1 | 1% |
| Japan | 1 | 1% |
| Other | 4 | 5% |
| Unknown | 22 | 30% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 38 | 52% |
| Members of the public | 34 | 47% |
| Science communicators (journalists, bloggers, editors) | 1 | 1% |
Mendeley readers
The data shown below were compiled from readership statistics for 173 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Unknown | 172 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 45 | 26% |
| Student > Ph. D. Student | 44 | 25% |
| Student > Master | 17 | 10% |
| Other | 12 | 7% |
| Professor > Associate Professor | 7 | 4% |
| Other | 26 | 15% |
| Unknown | 22 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 73 | 42% |
| Agricultural and Biological Sciences | 49 | 28% |
| Medicine and Dentistry | 8 | 5% |
| Computer Science | 4 | 2% |
| Chemistry | 4 | 2% |
| Other | 12 | 7% |
| Unknown | 23 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 46. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 March 2024.
All research outputs
#925,503
of 25,732,188 outputs
Outputs from Genome Biology
#625
of 4,509 outputs
Outputs of similar age
#18,728
of 329,317 outputs
Outputs of similar age from Genome Biology
#12
of 62 outputs
Altmetric has tracked 25,732,188 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,509 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,317 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.