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Redox signaling in pathophysiology of hypertension

Overview of attention for article published in Journal of Biomedical Science, September 2013
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2 X users
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3 Facebook pages

Citations

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Title
Redox signaling in pathophysiology of hypertension
Published in
Journal of Biomedical Science, September 2013
DOI 10.1186/1423-0127-20-69
Pubmed ID
Authors

Miroslava Majzunova, Ima Dovinova, Miroslav Barancik, Julie YH Chan

Abstract

Reactive oxygen species (ROS) are products of normal cellular metabolism and derive from various sources in different cellular compartments. Oxidative stress resultant from imbalance between ROS generation and antioxidant defense mechanisms is important in pathogenesis of cardiovascular diseases, such as hypertension, heart failure, atherosclerosis, diabetes, and cardiac hypertrophy. In this review we focus on hypertension and address sources of cellular ROS generation, mechanisms involved in regulation of radical homeostasis, superoxide dismutase isoforms in pathophysiology of hypertension; as well as radical intracellular signaling and phosphorylation processes in proteins of the affected cardiovascular tissues. Finally, we discuss the transcriptional factors involved in redox-sensitive gene transcription and antioxidant response, as well as their roles in hypertension.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 79 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 16 20%
Student > Ph. D. Student 9 11%
Student > Bachelor 9 11%
Researcher 7 9%
Professor 6 8%
Other 16 20%
Unknown 17 21%
Readers by discipline Count As %
Medicine and Dentistry 17 21%
Agricultural and Biological Sciences 13 16%
Biochemistry, Genetics and Molecular Biology 11 14%
Pharmacology, Toxicology and Pharmaceutical Science 6 8%
Environmental Science 3 4%
Other 10 13%
Unknown 20 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2014.
All research outputs
#14,388,865
of 25,374,917 outputs
Outputs from Journal of Biomedical Science
#603
of 1,101 outputs
Outputs of similar age
#108,781
of 213,376 outputs
Outputs of similar age from Journal of Biomedical Science
#7
of 9 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,101 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 213,376 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.