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Analysis of the genetic variation in mitochondrial DNA, Y-chromosome sequences, and MC1R sheds light on the ancestry of Nigerian indigenous pigs

Overview of attention for article published in Genetics Selection Evolution, June 2017
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Title
Analysis of the genetic variation in mitochondrial DNA, Y-chromosome sequences, and MC1R sheds light on the ancestry of Nigerian indigenous pigs
Published in
Genetics Selection Evolution, June 2017
DOI 10.1186/s12711-017-0326-1
Pubmed ID
Authors

Adeniyi C. Adeola, Olufunke O. Oluwole, Bukola M. Oladele, Temilola O. Olorungbounmi, Bamidele Boladuro, Sunday C. Olaogun, Lotanna M. Nneji, Oscar J. Sanke, Philip M. Dawuda, Ofelia G. Omitogun, Laurent Frantz, Robert W. Murphy, Hai-Bing Xie, Min-Sheng Peng, Ya-Ping Zhang

Abstract

The history of pig populations in Africa remains controversial due to insufficient evidence from archaeological and genetic data. Previously, a Western ancestry for West African pigs was reported based on loci that are involved in the determination of coat color. We investigated the genetic diversity of Nigerian indigenous pigs (NIP) by simultaneously analyzing variation in mitochondrial DNA (mtDNA), Y-chromosome sequence and the melanocortin receptor 1 (MC1R) gene. Median-joining network analysis of mtDNA D-loop sequences from 201 NIP and previously characterized loci clustered NIP with populations from the West (Europe/North Africa) and East/Southeast Asia. Analysis of partial sequences of the Y-chromosome in 57 Nigerian boars clustered NIP into lineage HY1. Finally, analysis of MC1R in 90 NIP resulted in seven haplotypes, among which the European wild boar haplotype was carried by one individual and the European dominant black by most of the other individuals (93%). The five remaining unique haplotypes differed by a single synonymous substitution from European wild type, European dominant black and Asian dominant black haplotypes. Our results demonstrate a European and East/Southeast Asian ancestry for NIP. Analyses of MC1R provide further evidence. Additional genetic analyses and archaeological studies may provide further insights into the history of African pig breeds. Our findings provide a valuable resource for future studies on whole-genome analyses of African pigs.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 37%
Researcher 4 15%
Student > Master 3 11%
Student > Bachelor 2 7%
Student > Doctoral Student 2 7%
Other 2 7%
Unknown 4 15%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 22%
Agricultural and Biological Sciences 6 22%
Veterinary Science and Veterinary Medicine 5 19%
Environmental Science 1 4%
Computer Science 1 4%
Other 2 7%
Unknown 6 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 June 2017.
All research outputs
#22,764,772
of 25,382,440 outputs
Outputs from Genetics Selection Evolution
#772
of 821 outputs
Outputs of similar age
#287,411
of 328,359 outputs
Outputs of similar age from Genetics Selection Evolution
#14
of 15 outputs
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