Title |
Successful combination of Rituximab and plasma exchange in the treatment of cryoglobulinemic vasculitis with skin ulcers: a case report
|
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Published in |
Cases Journal, July 2009
|
DOI | 10.4076/1757-1626-2-7859 |
Pubmed ID | |
Authors |
Tiziano Tallarita, Massimiliano Gagliano, Daniela Corona, Giuseppe Giuffrida, Alessia Giaquinta, Domenico Zerbo, Massimiliano Sorbello, Pierfrancesco Veroux, Massimiliano Veroux |
Abstract |
Type II mixed cryoglobulin syndrome is a systematic vasculitis mainly linked to immune complex deposition in several organs and to hepatitis C virus infection. Therapeutic strategies can target either the viral trigger hepatitis C virus if present, or pathogenic events downstream the triggering infection, e.g, the proliferation B-cells directly. Antiviral therapy should be considered as a first-line treatment in many HCV-positive patients. However, it may prove ineffective, contraindicated, or poorly tolerated. The other available treatment [such as cytotoxic agents, steroids] may lead to life-threatening complications and may be difficult to manage in the long term. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 5% |
Unknown | 18 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 3 | 16% |
Professor > Associate Professor | 3 | 16% |
Lecturer > Senior Lecturer | 2 | 11% |
Student > Postgraduate | 2 | 11% |
Student > Master | 2 | 11% |
Other | 4 | 21% |
Unknown | 3 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 58% |
Biochemistry, Genetics and Molecular Biology | 1 | 5% |
Agricultural and Biological Sciences | 1 | 5% |
Nursing and Health Professions | 1 | 5% |
Unknown | 5 | 26% |