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Development of a novel antimicrobial-releasing glass ionomer cement functionalized with chlorhexidine hexametaphosphate nanoparticles

Overview of attention for article published in Journal of Nanobiotechnology, January 2014
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Title
Development of a novel antimicrobial-releasing glass ionomer cement functionalized with chlorhexidine hexametaphosphate nanoparticles
Published in
Journal of Nanobiotechnology, January 2014
DOI 10.1186/1477-3155-12-3
Pubmed ID
Authors

Edward R Hook, Olivia J Owen, Candice A Bellis, James A Holder, Dominic J O’Sullivan, Michele E Barbour

Abstract

Glass ionomer cements (GICs) are a class of dental biomaterials. They have a wide range of uses including permanent restorations (fillings), cavity linings, fissure sealants and adhesives. One of the most common reasons for replacing a dental restoration is recurrent bacterial tooth decay around the margins of the biomaterial. Therefore, a dental biomaterial which creates a sustained antimicrobial environment around the restoration would be of considerable clinical benefit. In this manuscript, the formulation of a GIC containing novel antimicrobial nanoparticles composed of chlorhexidine hexametaphosphate at 1, 2, 5, 10 and 20% powder substitution by mass is reported. The aim is to create GICs which contain chlorhexidine-hexametaphosphate nanoparticles and characterize the nanoparticle size, morphology and charge and the release of chlorhexidine and fluoride, tensile strength and morphology of the GICs.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
Mexico 1 1%
Romania 1 1%
Unknown 84 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 20%
Student > Master 15 17%
Student > Bachelor 9 10%
Student > Doctoral Student 6 7%
Student > Postgraduate 6 7%
Other 13 15%
Unknown 21 24%
Readers by discipline Count As %
Medicine and Dentistry 36 41%
Materials Science 8 9%
Chemistry 7 8%
Engineering 4 5%
Nursing and Health Professions 3 3%
Other 7 8%
Unknown 23 26%