Title |
Good manufacturing practice-compliant isolation and culture of human umbilical cord blood-derived mesenchymal stem cells
|
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Published in |
Journal of Translational Medicine, February 2014
|
DOI | 10.1186/1479-5876-12-56 |
Pubmed ID | |
Authors |
Phuc Van Pham, Ngoc Bich Vu, Vuong Minh Pham, Nhung Hai Truong, Truc Le-Buu Pham, Loan Thi-Tung Dang, Tam Thanh Nguyen, Anh Nguyen-Tu Bui, Ngoc Kim Phan |
Abstract |
Mesenchymal stem cells (MSCs) are an attractive source of stem cells for clinical applications. These cells exhibit a multilineage differentiation potential and strong capacity for immune modulation. Thus, MSCs are widely used in cell therapy, tissue engineering, and immunotherapy. Because of important advantages, umbilical cord blood-derived MSCs (UCB-MSCs) have attracted interest for some time. However, the applications of UCB-MSCs are limited by the small number of recoverable UCB-MSCs and fetal bovine serum (FBS)-dependent expansion methods. Hence, this study aimed to establish a xenogenic and allogeneic supplement-free expansion protocol. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Mexico | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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France | 1 | <1% |
United Kingdom | 1 | <1% |
Sri Lanka | 1 | <1% |
Japan | 1 | <1% |
United States | 1 | <1% |
Unknown | 106 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 24 | 22% |
Student > Master | 24 | 22% |
Student > Ph. D. Student | 13 | 12% |
Student > Bachelor | 11 | 10% |
Student > Postgraduate | 7 | 6% |
Other | 15 | 14% |
Unknown | 17 | 15% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 26 | 23% |
Medicine and Dentistry | 25 | 23% |
Agricultural and Biological Sciences | 22 | 20% |
Engineering | 4 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 4% |
Other | 11 | 10% |
Unknown | 19 | 17% |