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X Demographics
Mendeley readers
Title |
Accelerating clinical development of HIV vaccine strategies: methodological challenges and considerations in constructing an optimised multi-arm phase I/II trial design
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Published in |
Trials, February 2014
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DOI | 10.1186/1745-6215-15-68 |
Pubmed ID | |
Authors |
Laura Richert, Adélaïde Doussau, Jean-Daniel Lelièvre, Vincent Arnold, Véronique Rieux, Amel Bouakane, Yves Lévy, Geneviève Chêne, Rodolphe Thiébaut, for the Vaccine Research Institute (VRI) |
Abstract |
Many candidate vaccine strategies against human immunodeficiency virus (HIV) infection are under study, but their clinical development is lengthy and iterative. To accelerate HIV vaccine development optimised trial designs are needed. We propose a randomised multi-arm phase I/II design for early stage development of several vaccine strategies, aiming at rapidly discarding those that are unsafe or non-immunogenic. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 29 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 8 | 28% |
Student > Master | 5 | 17% |
Student > Ph. D. Student | 5 | 17% |
Lecturer | 1 | 3% |
Student > Doctoral Student | 1 | 3% |
Other | 3 | 10% |
Unknown | 6 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 31% |
Biochemistry, Genetics and Molecular Biology | 3 | 10% |
Mathematics | 2 | 7% |
Agricultural and Biological Sciences | 2 | 7% |
Social Sciences | 2 | 7% |
Other | 3 | 10% |
Unknown | 8 | 28% |