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Interleukin-1β sequesters hypoxia inducible factor 2α to the primary cilium

Overview of attention for article published in Cilia, December 2013
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Citations

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Readers on

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44 Mendeley
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Title
Interleukin-1β sequesters hypoxia inducible factor 2α to the primary cilium
Published in
Cilia, December 2013
DOI 10.1186/2046-2530-2-17
Pubmed ID
Authors

Angus KT Wann, Clare L Thompson, J Paul Chapple, Martin M Knight

Abstract

The primary cilium coordinates signalling in development, health and disease. Previously we have shown that the cilium is essential for the anabolic response to loading and the inflammatory response to interleukin-1β (IL-1β). We have also shown the primary cilium elongates in response to IL-1β exposure. Both anabolic phenotype and inflammatory pathology are proposed to be dependent on hypoxia-inducible factor 2 alpha (HIF-2α). The present study tests the hypothesis that an association exists between the primary cilium and HIFs in inflammatory signalling.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 5%
United Kingdom 1 2%
Italy 1 2%
Unknown 40 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 25%
Researcher 8 18%
Professor > Associate Professor 5 11%
Student > Bachelor 3 7%
Student > Doctoral Student 2 5%
Other 8 18%
Unknown 7 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 10 23%
Biochemistry, Genetics and Molecular Biology 7 16%
Medicine and Dentistry 6 14%
Engineering 5 11%
Unspecified 2 5%
Other 3 7%
Unknown 11 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 February 2014.
All research outputs
#15,295,786
of 22,747,498 outputs
Outputs from Cilia
#61
of 91 outputs
Outputs of similar age
#192,600
of 307,388 outputs
Outputs of similar age from Cilia
#1
of 4 outputs
Altmetric has tracked 22,747,498 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 91 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,388 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them