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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Epigenetic silencing of miR-375 induces trastuzumab resistance in HER2-positive breast cancer by targeting IGF1R
|
|---|---|
| Published in |
BMC Cancer, February 2014
|
| DOI | 10.1186/1471-2407-14-134 |
| Pubmed ID | |
| Authors |
Xing-Ming Ye, Hua-Yu Zhu, Wen-Dong Bai, Ting Wang, Lei Wang, Ying Chen, An-Gang Yang, Lin-Tao Jia |
| Abstract |
Resistance to humanized monoclonal erbB2/HER2 antibody, trastuzumab (Herceptin), has become a pivotal obstacle for targeted therapy of HER2-positive breast cancers. The activation of alternative growth factor receptors, in particular, the insulin-like growth factor 1 receptor (IGF1R), represents a common feature of trastuzumab-refractory cells; however, the underlying mechanism remains elusive. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Argentina | 1 | 33% |
| United States | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 2% |
| Poland | 1 | 2% |
| Austria | 1 | 2% |
| Unknown | 61 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 30% |
| Student > Master | 11 | 17% |
| Researcher | 8 | 13% |
| Student > Bachelor | 5 | 8% |
| Student > Doctoral Student | 2 | 3% |
| Other | 8 | 13% |
| Unknown | 11 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 17 | 27% |
| Biochemistry, Genetics and Molecular Biology | 15 | 23% |
| Medicine and Dentistry | 11 | 17% |
| Computer Science | 2 | 3% |
| Environmental Science | 1 | 2% |
| Other | 5 | 8% |
| Unknown | 13 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2014.
All research outputs
#13,709,189
of 22,747,498 outputs
Outputs from BMC Cancer
#3,127
of 8,273 outputs
Outputs of similar age
#113,110
of 221,189 outputs
Outputs of similar age from BMC Cancer
#56
of 141 outputs
Altmetric has tracked 22,747,498 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,273 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 221,189 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 141 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.