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Synthesis, identification and in vivo studies of tumor-targeting agent peptide doxorubicin (PDOX) to treat peritoneal carcinomatosis of gastric cancer with similar efficacy but reduced toxicity

Overview of attention for article published in Molecular Cancer, March 2014
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Title
Synthesis, identification and in vivo studies of tumor-targeting agent peptide doxorubicin (PDOX) to treat peritoneal carcinomatosis of gastric cancer with similar efficacy but reduced toxicity
Published in
Molecular Cancer, March 2014
DOI 10.1186/1476-4598-13-44
Pubmed ID
Authors

Li Tang, Rui Duan, Yan-jun Zhong, Raymond A Firestone, Ya-ping Hong, Ji-guo Li, Yan-chao Xin, Han-lin Wu, Yan Li

Abstract

This work aimed to synthesize a cathepsin B (CTSB)-cleavable tumor-targeting prodrug peptide doxorubicin (PDOX) and study the in vivo efficacy and toxicities on an animal model of gastric peritoneal carcinomatosis (PC).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Poland 1 4%
Unknown 27 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 25%
Student > Ph. D. Student 5 18%
Other 3 11%
Student > Bachelor 2 7%
Student > Doctoral Student 1 4%
Other 2 7%
Unknown 8 29%
Readers by discipline Count As %
Medicine and Dentistry 8 29%
Chemistry 4 14%
Psychology 2 7%
Biochemistry, Genetics and Molecular Biology 1 4%
Sports and Recreations 1 4%
Other 3 11%
Unknown 9 32%