Title |
Genome-wide association and genomic prediction for host response to porcine reproductive and respiratory syndrome virus infection
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Published in |
Genetics Selection Evolution, March 2014
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DOI | 10.1186/1297-9686-46-18 |
Pubmed ID | |
Authors |
Nicholas J Boddicker, Angelica Bjorkquist, Raymond RR Rowland, Joan K Lunney, James M Reecy, Jack CM Dekkers |
Abstract |
Host genetics has been shown to play a role in porcine reproductive and respiratory syndrome (PRRS), which is the most economically important disease in the swine industry. A region on Sus scrofa chromosome (SSC) 4 has been previously reported to have a strong association with serum viremia and weight gain in pigs experimentally infected with the PRRS virus (PRRSV). The objective here was to identify haplotypes associated with the favorable phenotype, investigate additional genomic regions associated with host response to PRRSV, and to determine the predictive ability of genomic estimated breeding values (GEBV) based on the SSC4 region and based on the rest of the genome. Phenotypic data and 60 K SNP genotypes from eight trials of ~200 pigs from different commercial crosses were used to address these objectives. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 3% |
Unknown | 74 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 17 | 22% |
Researcher | 17 | 22% |
Student > Master | 8 | 11% |
Student > Doctoral Student | 5 | 7% |
Other | 3 | 4% |
Other | 9 | 12% |
Unknown | 17 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 33 | 43% |
Veterinary Science and Veterinary Medicine | 8 | 11% |
Biochemistry, Genetics and Molecular Biology | 7 | 9% |
Medicine and Dentistry | 3 | 4% |
Unspecified | 2 | 3% |
Other | 3 | 4% |
Unknown | 20 | 26% |