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Tumor cells with low proteasome subunit expression predict overall survival in head and neck cancer patients

Overview of attention for article published in BMC Cancer, March 2014
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Title
Tumor cells with low proteasome subunit expression predict overall survival in head and neck cancer patients
Published in
BMC Cancer, March 2014
DOI 10.1186/1471-2407-14-152
Pubmed ID
Authors

Chann Lagadec, Erina Vlashi, Sunita Bhuta, Chi Lai, Paul Mischel, Martin Werner, Michael Henke, Frank Pajonk

Abstract

Experimental and clinical data suggest that solid cancers contain treatment-resistant cancer stem cells that will impair treatment efficacy. The objective of this study was to investigate if head and neck squamous cell carcinoma (HNSCC) also contain cancer stem cells that can be identified by low 26S proteasome activity and if their presence correlates to clinical outcome.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Germany 1 2%
Unknown 47 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 16%
Student > Bachelor 8 16%
Student > Ph. D. Student 7 14%
Researcher 6 12%
Professor > Associate Professor 3 6%
Other 12 24%
Unknown 5 10%
Readers by discipline Count As %
Medicine and Dentistry 18 37%
Biochemistry, Genetics and Molecular Biology 11 22%
Agricultural and Biological Sciences 8 16%
Nursing and Health Professions 2 4%
Computer Science 1 2%
Other 4 8%
Unknown 5 10%