Title |
Utility of intranasal Ketamine and Midazolam to perform gastric aspirates in children: a double-blind, placebo controlled, randomized study
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Published in |
BMC Pediatrics, March 2014
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DOI | 10.1186/1471-2431-14-67 |
Pubmed ID | |
Authors |
Danilo Buonsenso, Giovanni Barone, Piero Valentini, Filomena Pierri, Riccardo Riccardi, Antonio Chiaretti |
Abstract |
We performed a prospective, randomized, placebo-controlled study aimed to evaluate the efficacy and safety of a sedation protocol based on intranasal Ketamine and Midazolam (INKM) administered by a mucosal atomizer device in uncooperative children undergoing gastric aspirates for suspected tuberculosis. Primary outcome: evaluation of Modified Objective Pain Score (MOPS) reduction in children undergoing INKM compared to the placebo group. Secondary outcomes: evaluation of safety of INKM protocol, start time sedation effect, duration of sedation and evaluation of parents and doctors' satisfaction about the procedure. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | 29% |
Unknown | 5 | 71% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 71% |
Practitioners (doctors, other healthcare professionals) | 2 | 29% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 1% |
Unknown | 73 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 15% |
Student > Master | 7 | 9% |
Student > Bachelor | 7 | 9% |
Student > Postgraduate | 6 | 8% |
Other | 4 | 5% |
Other | 11 | 15% |
Unknown | 28 | 38% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 30 | 41% |
Nursing and Health Professions | 3 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Agricultural and Biological Sciences | 2 | 3% |
Arts and Humanities | 1 | 1% |
Other | 6 | 8% |
Unknown | 30 | 41% |