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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Chemotherapy and tumor microenvironment of pancreatic cancer
|
|---|---|
| Published in |
Cancer Cell International, July 2017
|
| DOI | 10.1186/s12935-017-0437-3 |
| Pubmed ID | |
| Authors |
Qiaofei Liu, Quan Liao, Yupei Zhao |
| Abstract |
Pancreatic cancer is an extremely dismal malignance. Chemotherapy has been widely applied to treat this intractable tumor. It has exclusive tumor microenvironment (TME), characterized by dense desmoplasia and profound infiltrations of immunosuppressive cells. Interactions between stromal cells and cancer cells play vital roles to affect the biological behaviors of pancreatic cancer. Targeting the stromal components of pancreatic cancer has shown promising results. In addition to the direct toxic effects of chemotherapeutic drugs on cancer cells, they can also remodel the TME, eventually affecting their efficacy. Herein, we reviewed the following four aspects; (1) clinical landmark advances of chemotherapy in pancreatic cancer, since 2000; (2) interactions and mechanisms between stromal cells and pancreatic cancer cells; (3) remodeling effects and mechanisms of chemotherapy on TME; (4) targeting stromal components in pancreatic cancer. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 7 | 70% |
| United Kingdom | 1 | 10% |
| Unknown | 2 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 90% |
| Scientists | 1 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 150 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 150 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 31 | 21% |
| Student > Bachelor | 21 | 14% |
| Student > Master | 20 | 13% |
| Researcher | 18 | 12% |
| Professor > Associate Professor | 9 | 6% |
| Other | 26 | 17% |
| Unknown | 25 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 37 | 25% |
| Biochemistry, Genetics and Molecular Biology | 25 | 17% |
| Agricultural and Biological Sciences | 17 | 11% |
| Immunology and Microbiology | 15 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 12 | 8% |
| Other | 14 | 9% |
| Unknown | 30 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 July 2017.
All research outputs
#4,494,701
of 22,986,950 outputs
Outputs from Cancer Cell International
#475
of 1,812 outputs
Outputs of similar age
#78,878
of 313,312 outputs
Outputs of similar age from Cancer Cell International
#2
of 13 outputs
Altmetric has tracked 22,986,950 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,812 research outputs from this source. They receive a mean Attention Score of 3.9. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,312 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.