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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Rewiring of regenerated axons by combining treadmill training with semaphorin3A inhibition
|
|---|---|
| Published in |
Molecular Brain, March 2014
|
| DOI | 10.1186/1756-6606-7-14 |
| Pubmed ID | |
| Authors |
Liang Zhang, Shinjiro Kaneko, Kaoru Kikuchi, Akihiko Sano, Miho Maeda, Akiyoshi Kishino, Shinsuke Shibata, Masahiko Mukaino, Yoshiaki Toyama, Meigen Liu, Toru Kimura, Hideyuki Okano, Masaya Nakamura |
| Abstract |
Rats exhibit extremely limited motor function recovery after total transection of the spinal cord (SCT). We previously reported that SM-216289, a semaphorin3A inhibitor, enhanced axon regeneration and motor function recovery in SCT adult rats. However, these effects were limited because most regenerated axons likely do not connect to the right targets. Thus, rebuilding the appropriate connections for regenerated axons may enhance recovery. In this study, we combined semaphorin3A inhibitor treatment with extensive treadmill training to determine whether combined treatment would further enhance the "rewiring" of regenerated axons. In this study, which aimed for clinical applicability, we administered a newly developed, potent semaphorin3A inhibitor, SM-345431 (Vinaxanthone), using a novel drug delivery system that enables continuous drug delivery over the period of the experiment. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 33% |
| Ireland | 1 | 17% |
| United States | 1 | 17% |
| Unknown | 2 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 67% |
| Science communicators (journalists, bloggers, editors) | 2 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 2% |
| Unknown | 60 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 13 | 21% |
| Student > Bachelor | 9 | 15% |
| Researcher | 9 | 15% |
| Other | 5 | 8% |
| Student > Doctoral Student | 4 | 7% |
| Other | 9 | 15% |
| Unknown | 12 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 23% |
| Neuroscience | 10 | 16% |
| Agricultural and Biological Sciences | 9 | 15% |
| Biochemistry, Genetics and Molecular Biology | 4 | 7% |
| Psychology | 2 | 3% |
| Other | 9 | 15% |
| Unknown | 13 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 March 2014.
All research outputs
#1,638,675
of 22,747,498 outputs
Outputs from Molecular Brain
#41
of 1,106 outputs
Outputs of similar age
#17,674
of 220,762 outputs
Outputs of similar age from Molecular Brain
#1
of 19 outputs
Altmetric has tracked 22,747,498 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,106 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 220,762 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.