Title |
Drug2Gene: an exhaustive resource to explore effectively the drug-target relation network
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Published in |
BMC Bioinformatics, March 2014
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DOI | 10.1186/1471-2105-15-68 |
Pubmed ID | |
Authors |
Helge G Roider, Nadia Pavlova, Ivaylo Kirov, Stoyan Slavov, Todor Slavov, Zlatyo Uzunov, Bertram Weiss |
Abstract |
Information about drug-target relations is at the heart of drug discovery. There are now dozens of databases providing drug-target interaction data with varying scope, and focus. Therefore, and due to the large chemical space, the overlap of the different data sets is surprisingly small. As searching through these sources manually is cumbersome, time-consuming and error-prone, integrating all the data is highly desirable. Despite a few attempts, integration has been hampered by the diversity of descriptions of compounds, and by the fact that the reported activity values, coming from different data sets, are not always directly comparable due to usage of different metrics or data formats. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 9% |
Germany | 1 | 9% |
Canada | 1 | 9% |
Norway | 1 | 9% |
Bulgaria | 1 | 9% |
Japan | 1 | 9% |
Unknown | 5 | 45% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 64% |
Scientists | 4 | 36% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 4% |
Germany | 2 | 3% |
Netherlands | 1 | 1% |
Bulgaria | 1 | 1% |
Belgium | 1 | 1% |
United Kingdom | 1 | 1% |
Russia | 1 | 1% |
Luxembourg | 1 | 1% |
Unknown | 64 | 85% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 20 | 27% |
Student > Ph. D. Student | 16 | 21% |
Student > Master | 11 | 15% |
Professor | 7 | 9% |
Student > Bachelor | 4 | 5% |
Other | 11 | 15% |
Unknown | 6 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 24 | 32% |
Computer Science | 13 | 17% |
Chemistry | 9 | 12% |
Biochemistry, Genetics and Molecular Biology | 8 | 11% |
Medicine and Dentistry | 4 | 5% |
Other | 9 | 12% |
Unknown | 8 | 11% |