Title |
A Key Role of the Basal Ganglia in Pain and Analgesia - Insights Gained through Human Functional Imaging
|
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Published in |
Molecular Pain, January 2010
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DOI | 10.1186/1744-8069-6-27 |
Pubmed ID | |
Authors |
David Borsook, Jaymin Upadhyay, Eric H Chudler, Lino Becerra |
Abstract |
The basal ganglia (BG) are composed of several nuclei involved in neural processing related to the execution of motor, cognitive and emotional activities. Preclinical and clinical data have implicated a role for these structures in pain processing. Recently neuroimaging has added important information on BG activation in conditions of acute pain, chronic pain and as a result of drug effects. Our current understanding of alterations in cortical and sub-cortical regions in pain suggests that the BG are uniquely involved in thalamo-cortico-BG loops to integrate many aspects of pain. These include the integration of motor, emotional, autonomic and cognitive responses to pain. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
United Kingdom | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 4 | 1% |
Chile | 3 | 1% |
Netherlands | 2 | <1% |
Canada | 2 | <1% |
Brazil | 2 | <1% |
Japan | 2 | <1% |
Turkey | 1 | <1% |
Denmark | 1 | <1% |
Switzerland | 1 | <1% |
Other | 2 | <1% |
Unknown | 263 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 58 | 20% |
Researcher | 58 | 20% |
Student > Bachelor | 28 | 10% |
Student > Master | 25 | 9% |
Professor > Associate Professor | 17 | 6% |
Other | 60 | 21% |
Unknown | 37 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 70 | 25% |
Neuroscience | 56 | 20% |
Psychology | 36 | 13% |
Agricultural and Biological Sciences | 27 | 10% |
Engineering | 9 | 3% |
Other | 32 | 11% |
Unknown | 53 | 19% |