↓ Skip to main content

Thrifty metabolic programming in rats is induced by both maternal undernutrition and postnatal leptin treatment, but masked in the presence of both: implications for models of developmental…

Overview of attention for article published in BMC Genomics, January 2014
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

Mentioned by

googleplus
4 Google+ users

Citations

dimensions_citation
32 Dimensions

Readers on

mendeley
87 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Thrifty metabolic programming in rats is induced by both maternal undernutrition and postnatal leptin treatment, but masked in the presence of both: implications for models of developmental programming
Published in
BMC Genomics, January 2014
DOI 10.1186/1471-2164-15-49
Pubmed ID
Authors

Peter JI Ellis, Tiffany J Morris, Benjamin M Skinner, Carole A Sargent, Mark H Vickers, Peter D Gluckman, Stewart Gilmour, Nabeel A Affara

Abstract

Maternal undernutrition leads to an increased risk of metabolic disorders in offspring including obesity and insulin resistance, thought to be due to a programmed thrifty phenotype which is inappropriate for a subsequent richer nutritional environment. In a rat model, both male and female offspring of undernourished mothers are programmed to become obese, however postnatal leptin treatment gives discordant results between males and females. Leptin treatment is able to rescue the adverse programming effects in the female offspring of undernourished mothers, but not in their male offspring. Additionally, in these rats, postnatal leptin treatment of offspring from normally-nourished mothers programmes their male offspring to develop obesity in later life, while there is no comparable effect in their female offspring.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Unknown 86 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 16%
Student > Bachelor 13 15%
Researcher 10 11%
Other 6 7%
Student > Doctoral Student 6 7%
Other 22 25%
Unknown 16 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 21 24%
Biochemistry, Genetics and Molecular Biology 16 18%
Medicine and Dentistry 9 10%
Nursing and Health Professions 6 7%
Immunology and Microbiology 4 5%
Other 13 15%
Unknown 18 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 March 2014.
All research outputs
#6,403,829
of 22,749,166 outputs
Outputs from BMC Genomics
#2,873
of 10,634 outputs
Outputs of similar age
#76,185
of 305,604 outputs
Outputs of similar age from BMC Genomics
#139
of 442 outputs
Altmetric has tracked 22,749,166 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 10,634 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,604 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 442 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.