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Genes with a large intronic burden show greater evolutionary conservation on the protein level

Overview of attention for article published in BMC Ecology and Evolution, March 2014
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3 X users

Citations

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73 Mendeley
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1 CiteULike
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Title
Genes with a large intronic burden show greater evolutionary conservation on the protein level
Published in
BMC Ecology and Evolution, March 2014
DOI 10.1186/1471-2148-14-50
Pubmed ID
Authors

Olga Gorlova, Alexey Fedorov, Christopher Logothetis, Christopher Amos, Ivan Gorlov

Abstract

The existence of introns in eukaryotic genes is believed to provide an evolutionary advantage by increasing protein diversity through exon shuffling and alternative splicing. However, this eukaryotic feature is associated with the necessity of exclusion of intronic sequences, which requires considerable energy expenditure and can lead to splicing errors. The relationship between intronic burden and evolution is poorly understood. The goal of this study was to analyze the relationship between the intronic burden and the level of evolutionary conservation of the gene.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 73 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 4%
United Kingdom 1 1%
Spain 1 1%
France 1 1%
Unknown 67 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 23%
Researcher 15 21%
Student > Bachelor 12 16%
Student > Master 7 10%
Student > Postgraduate 4 5%
Other 9 12%
Unknown 9 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 33 45%
Biochemistry, Genetics and Molecular Biology 20 27%
Computer Science 4 5%
Medicine and Dentistry 3 4%
Business, Management and Accounting 1 1%
Other 2 3%
Unknown 10 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 March 2014.
All research outputs
#15,740,207
of 25,374,647 outputs
Outputs from BMC Ecology and Evolution
#2,638
of 3,714 outputs
Outputs of similar age
#125,572
of 235,983 outputs
Outputs of similar age from BMC Ecology and Evolution
#41
of 70 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,714 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.5. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 235,983 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 70 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.