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Etiology and prognosis of acute viral encephalitis and meningitis in Chinese children: a multicentre prospective study

Overview of attention for article published in BMC Infectious Diseases, July 2017
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

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Title
Etiology and prognosis of acute viral encephalitis and meningitis in Chinese children: a multicentre prospective study
Published in
BMC Infectious Diseases, July 2017
DOI 10.1186/s12879-017-2572-9
Pubmed ID
Authors

Junhong Ai, Zhengde Xie, Gang Liu, Zongbo Chen, Yong Yang, Yuning Li, Jing Chen, Guo Zheng, Kunling Shen

Abstract

In China, there were few studies about the pathogens of acute viral encephalitis and meningitis in children in recent years. The aims of this study were to characterize the etiology and prognosis of acute viral encephalitis and meningitis in Chinese children. This was a multicentre prospective study. Two hundred and sixty one viral encephalitis patients and 285 viral meningitis patients were enrolled. The mean age of viral encephalitis and meningitis were 5.88 ± 3.60 years and 6.39 ± 3.57 years, respectively. Real-time reverse transcription PCR and multiplex PCR were used to detect human enteroviruses and herpes viruses in cerebrospinal fluid (CSF) of patients with encephalitis or meningitis. The enzyme-linked immune absorbent assay (ELISA) was used for detecting IgM antibody against Japanese encephalitis virus (JEV) in CSF and against mumps virus, tick-borne encephalitis virus (TBEV), dengue virus and rubella virus in acute serum. The clinical and outcome data were collected during patients' hospitalization. The etiology of viral encephalitis was confirmed in 52.5% patients. The primary pathogen was human enteroviruses (27.7%) in viral encephalitis. The incidence of sequelae and the fatality rate of viral encephalitis with confirmed etiology were 7.5% and 0.8%, respectively. The etiology of viral meningitis was identified in 42.8% cases. The leading pathogen was also human enteroviruses (37.7%) in viral meningitis. The prognosis of viral meningitis was favorable with only 0.7% patients had neurological sequelae. Human enteroviruses were the leading cause both in acute viral encephalitis and viral meningitis in children. The incidence of sequelae and fatality rate of viral encephalitis with confirmed etiology were 7.5% and 0.8%, respectively. The prognosis of viral meningitis was favorable compared to viral encephalitis.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 155 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 155 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 20 13%
Student > Bachelor 20 13%
Student > Master 17 11%
Other 11 7%
Student > Postgraduate 10 6%
Other 29 19%
Unknown 48 31%
Readers by discipline Count As %
Medicine and Dentistry 55 35%
Biochemistry, Genetics and Molecular Biology 12 8%
Immunology and Microbiology 10 6%
Neuroscience 7 5%
Nursing and Health Professions 4 3%
Other 13 8%
Unknown 54 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 June 2022.
All research outputs
#2,404,633
of 22,707,247 outputs
Outputs from BMC Infectious Diseases
#714
of 7,650 outputs
Outputs of similar age
#48,043
of 311,658 outputs
Outputs of similar age from BMC Infectious Diseases
#15
of 187 outputs
Altmetric has tracked 22,707,247 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,650 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,658 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 187 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.