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Inhibition of G Protein-Coupled P2Y2 Receptor Induced Analgesia in a Rat Model of Trigeminal Neuropathic Pain

Overview of attention for article published in Molecular Pain, January 2014
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Title
Inhibition of G Protein-Coupled P2Y2 Receptor Induced Analgesia in a Rat Model of Trigeminal Neuropathic Pain
Published in
Molecular Pain, January 2014
DOI 10.1186/1744-8069-10-21
Pubmed ID
Authors

Na Li, Zhan-ying Lu, Li-hua Yu, Geoffrey Burnstock, Xiao-ming Deng, Bei Ma

Abstract

ATP and P2X receptors play important roles in the modulation of trigeminal neuropathic pain, while the role of G protein-coupled P2Y₂ receptors and the underlying mechanisms are less clear. The threshold and frequency of action potentials, fast inactivating transient K+ channels (IA) are important regulators of membrane excitability in sensory neurons because of its vital role in the control of the spike onset. In this study, pain behavior tests, QT-RT-PCR, immunohistochemical staining, and patch-clamp recording, were used to investigate the role of P2Y₂ receptors in pain behaviour.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Portugal 1 2%
Unknown 41 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 37%
Student > Master 5 12%
Professor 4 9%
Researcher 4 9%
Student > Bachelor 3 7%
Other 5 12%
Unknown 6 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 30%
Medicine and Dentistry 8 19%
Biochemistry, Genetics and Molecular Biology 4 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Psychology 2 5%
Other 4 9%
Unknown 10 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 March 2014.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from Molecular Pain
#477
of 669 outputs
Outputs of similar age
#243,187
of 319,280 outputs
Outputs of similar age from Molecular Pain
#35
of 58 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,280 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.