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Irradiation of the potential cancer stem cell niches in the adult brain improves progression-free survival of patients with malignant glioma

Overview of attention for article published in BMC Cancer, July 2010
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1 X user

Citations

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103 Mendeley
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Title
Irradiation of the potential cancer stem cell niches in the adult brain improves progression-free survival of patients with malignant glioma
Published in
BMC Cancer, July 2010
DOI 10.1186/1471-2407-10-384
Pubmed ID
Authors

Patrick Evers, Percy P Lee, John DeMarco, Nzhde Agazaryan, James W Sayre, Michael Selch, Frank Pajonk

Abstract

Glioblastoma is the most common brain tumor in adults. The mechanisms leading to glioblastoma are not well understood but animal studies support that inactivation of tumor suppressor genes in neural stem cells (NSC) is required and sufficient to induce glial cancers. This suggests that the NSC niches in the brain may harbor cancer stem cells (CSCs), Thus providing novel therapy targets. We hypothesize that higher radiation doses to these NSC niches improve patient survival by eradicating CSCs.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 103 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
United Kingdom 1 <1%
Unknown 100 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 23 22%
Student > Ph. D. Student 20 19%
Student > Master 9 9%
Student > Bachelor 8 8%
Other 7 7%
Other 22 21%
Unknown 14 14%
Readers by discipline Count As %
Medicine and Dentistry 38 37%
Agricultural and Biological Sciences 28 27%
Neuroscience 9 9%
Biochemistry, Genetics and Molecular Biology 5 5%
Physics and Astronomy 3 3%
Other 4 4%
Unknown 16 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 March 2014.
All research outputs
#15,296,915
of 22,749,166 outputs
Outputs from BMC Cancer
#4,106
of 8,273 outputs
Outputs of similar age
#76,397
of 94,519 outputs
Outputs of similar age from BMC Cancer
#43
of 55 outputs
Altmetric has tracked 22,749,166 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,273 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 94,519 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 55 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.