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Mendeley readers
Title |
Validation of miRNA-mRNA interactions by electrophoretic mobility shift assays
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Published in |
BMC Research Notes, November 2013
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DOI | 10.1186/1756-0500-6-454 |
Pubmed ID | |
Authors |
Anna Solé, Núria Mencia, Xenia Villalobos, Véronique Noé, Carlos J Ciudad |
Abstract |
MicroRNAs are small non-coding RNAs involved in gene expression regulation by targeting specific regions in the 3'-UTR of the mRNA of their target genes. This binding leads to a decrease in the protein levels of such genes either by mRNA degradation or mRNA destabilization and translation inhibition. The interaction between a miRNA and its target mRNAs is usually studied by co-transfection of a reporter expression vector containing the 3'-UTR region of the mRNA and an inhibitory or precursor molecule for the miRNA. This approach, however, does not measure the direct and physical interaction between a miRNA and a specific mRNA. |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 28 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 10 | 36% |
Professor | 4 | 14% |
Student > Bachelor | 3 | 11% |
Researcher | 3 | 11% |
Student > Doctoral Student | 2 | 7% |
Other | 4 | 14% |
Unknown | 2 | 7% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 12 | 43% |
Agricultural and Biological Sciences | 9 | 32% |
Chemistry | 3 | 11% |
Unspecified | 1 | 4% |
Medicine and Dentistry | 1 | 4% |
Other | 0 | 0% |
Unknown | 2 | 7% |