Title |
Antihyperlipidemic effects of Pleurotus ostreatus (oyster mushrooms) in HIV-infected individuals taking antiretroviral therapy
|
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Published in |
BMC Complementary Medicine and Therapies, August 2011
|
DOI | 10.1186/1472-6882-11-60 |
Pubmed ID | |
Authors |
Donald I Abrams, Paul Couey, Starley B Shade, Mary Ellen Kelly, Nnemdi Kamanu-Elias, Paul Stamets |
Abstract |
Antiretroviral treatment (ART) regimens in HIV patients commonly cause significant lipid elevations, including increases in both triglycerides and cholesterol. Standard treatments for hypercholesterolemia include the HMG CoA reductase inhibitors, or "statins." Because many ART agents and statins share a common metabolic pathway that uses the cytochrome P450 enzyme system, coadministration of ART with statins could increase statin plasma levels significantly. The oyster mushroom, Pleurotus ostreatus, has been shown in animal models to decrease lipid levels--a finding that has been supported by preliminary data in a small human trial. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 2 | 40% |
Italy | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 80% |
Unknown | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Peru | 2 | 2% |
Unknown | 108 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 20 | 18% |
Student > Master | 14 | 13% |
Researcher | 13 | 12% |
Student > Postgraduate | 9 | 8% |
Student > Ph. D. Student | 9 | 8% |
Other | 20 | 18% |
Unknown | 25 | 23% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 26 | 24% |
Medicine and Dentistry | 23 | 21% |
Biochemistry, Genetics and Molecular Biology | 5 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 5% |
Nursing and Health Professions | 4 | 4% |
Other | 14 | 13% |
Unknown | 33 | 30% |