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Treatment effects of recombinant human soluble thrombomodulin in patients with severe sepsis: a historical control study

Overview of attention for article published in Critical Care, May 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (79th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

Mentioned by

patent
4 patents
peer_reviews
1 peer review site

Citations

dimensions_citation
117 Dimensions

Readers on

mendeley
63 Mendeley
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Title
Treatment effects of recombinant human soluble thrombomodulin in patients with severe sepsis: a historical control study
Published in
Critical Care, May 2011
DOI 10.1186/cc10228
Pubmed ID
Authors

Kazuma Yamakawa, Satoshi Fujimi, Tomoyoshi Mohri, Hiroki Matsuda, Yasushi Nakamori, Tomoya Hirose, Osamu Tasaki, Hiroshi Ogura, Yasuyuki Kuwagata, Toshimitsu Hamasaki, Takeshi Shimazu

Abstract

Cross-talk between the coagulation system and inflammatory reactions during sepsis causes organ damage followed by multiple organ dysfunction syndrome or even death. Therefore, anticoagulant therapies have been expected to be beneficial in the treatment of severe sepsis. Recombinant human soluble thrombomodulin (rhTM) binds to thrombin to inactivate coagulation, and the thrombin-rhTM complex activates protein C to produce activated protein C. The purpose of this study was to examine the efficacy of rhTM for treating patients with sepsis-induced disseminated intravascular coagulation (DIC).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 3 5%
Japan 2 3%
United States 1 2%
Unknown 57 90%

Demographic breakdown

Readers by professional status Count As %
Other 18 29%
Researcher 9 14%
Student > Ph. D. Student 7 11%
Student > Doctoral Student 4 6%
Student > Master 4 6%
Other 11 17%
Unknown 10 16%
Readers by discipline Count As %
Medicine and Dentistry 43 68%
Agricultural and Biological Sciences 5 8%
Nursing and Health Professions 2 3%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Business, Management and Accounting 1 2%
Other 0 0%
Unknown 11 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 September 2023.
All research outputs
#4,835,157
of 25,371,288 outputs
Outputs from Critical Care
#3,282
of 6,554 outputs
Outputs of similar age
#23,708
of 121,335 outputs
Outputs of similar age from Critical Care
#15
of 47 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 121,335 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 79% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.