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Genotype and diet shape resistance and tolerance across distinct phases of bacterial infection

Overview of attention for article published in BMC Ecology and Evolution, March 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

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14 X users

Citations

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122 Dimensions

Readers on

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133 Mendeley
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Title
Genotype and diet shape resistance and tolerance across distinct phases of bacterial infection
Published in
BMC Ecology and Evolution, March 2014
DOI 10.1186/1471-2148-14-56
Pubmed ID
Authors

Virginia M Howick, Brian P Lazzaro

Abstract

Host defense against pathogenic infection is composed of resistance and tolerance. Resistance is the ability of the host to limit a pathogen burden, whereas tolerance is the ability to limit the deleterious effects of a given pathogen burden. This distinction recognizes that the fittest host does not necessarily have the most aggressive immune system, suggesting that host-pathogen co-evolution involves more than an escalating arms race between pathogen virulence factors and host antimicrobial activity. How a host balances resistance and tolerance and how this balance influences the evolution of host defense remains unanswered. In order to determine how genotype-by-diet interactions and evolutionary costs of each strategy may constrain the evolution of host defense, we measured survival, fecundity, and pathogen burden over five days in ten genotypes of Drosophila melanogaster reared on two diets and infected with the Gram-negative bacterial pathogen Providencia rettgeri.

X Demographics

X Demographics

The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 133 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Switzerland 1 <1%
Unknown 130 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 42 32%
Researcher 24 18%
Student > Master 18 14%
Student > Bachelor 11 8%
Professor > Associate Professor 7 5%
Other 15 11%
Unknown 16 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 71 53%
Biochemistry, Genetics and Molecular Biology 21 16%
Environmental Science 7 5%
Immunology and Microbiology 7 5%
Medicine and Dentistry 3 2%
Other 3 2%
Unknown 21 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 May 2014.
All research outputs
#3,403,256
of 25,420,980 outputs
Outputs from BMC Ecology and Evolution
#911
of 3,714 outputs
Outputs of similar age
#32,820
of 237,444 outputs
Outputs of similar age from BMC Ecology and Evolution
#17
of 72 outputs
Altmetric has tracked 25,420,980 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,714 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.5. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 237,444 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 72 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.