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Early tissue responses to zoledronate, locally delivered by bone screw, into a compromised cancellous bone site: a pilot study

Overview of attention for article published in BMC Musculoskeletal Disorders, March 2014
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Mentioned by

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3 tweeters

Citations

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12 Dimensions

Readers on

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27 Mendeley
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Title
Early tissue responses to zoledronate, locally delivered by bone screw, into a compromised cancellous bone site: a pilot study
Published in
BMC Musculoskeletal Disorders, March 2014
DOI 10.1186/1471-2474-15-97
Pubmed ID
Authors

Joerg Arnoldi, Antoine Alves, Philip Procter

Abstract

In fracture treatment, adequate fixation of implants is crucial to long-term clinical performance. Bisphosphonates (BP), potent inhibitors of osteoclastic bone resorption, are known to increase peri-implant bone mass and accelerate primary fixation. However, adverse effects are associated with systemic use of BPs. Thus, Zoledronic acid (ZOL) a potent BP was loaded on bone screws and evaluated in a local delivery model. Whilst mid- to long-term effects are already reported, early cellular events occurring at the implant/bone interface are not well described. The present study investigated early tissue responses to ZOL locally delivered, by bone screw, into a compromised cancellous bone site.

Twitter Demographics

The data shown below were collected from the profiles of 3 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 22%
Student > Master 6 22%
Student > Doctoral Student 3 11%
Researcher 3 11%
Student > Bachelor 3 11%
Other 4 15%
Unknown 2 7%
Readers by discipline Count As %
Medicine and Dentistry 15 56%
Engineering 4 15%
Biochemistry, Genetics and Molecular Biology 2 7%
Materials Science 2 7%
Neuroscience 1 4%
Other 0 0%
Unknown 3 11%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 July 2015.
All research outputs
#13,347,311
of 21,365,584 outputs
Outputs from BMC Musculoskeletal Disorders
#1,992
of 3,766 outputs
Outputs of similar age
#107,144
of 206,322 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#1
of 1 outputs
Altmetric has tracked 21,365,584 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,766 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one is in the 43rd percentile – i.e., 43% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 206,322 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them