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Immunohistochemical localization and mRNA quantification of osteopontin and Tamm-Horsfall protein in canine renal tissue after potassium oxalate injection

Overview of attention for article published in BMC Veterinary Research, March 2014
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2 X users
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1 peer review site

Citations

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12 Dimensions

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13 Mendeley
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Title
Immunohistochemical localization and mRNA quantification of osteopontin and Tamm-Horsfall protein in canine renal tissue after potassium oxalate injection
Published in
BMC Veterinary Research, March 2014
DOI 10.1186/1746-6148-10-70
Pubmed ID
Authors

Walaa Mohamaden, Heng Wang, Huawei Guan, Xia Meng, Jianji Li

Abstract

Urinary macromolecules contribute to promoting or inhibiting crystal retention in renal tissue and stone formation. Osteopontin (OPN) and Tamm-Horsfall protein (THP) are the most important proteins involved in this process. Although these two proteins were discovered a long time ago, their role in setting kidney stone formation has not yet been fully investigated. We conducted a study to explore the role of OPN and THP in canine renal oxalosis. Ten dogs were carefully examined prior to the study. Six dogs were assigned to the treatment group and were injected intravenously with 0.5 M potassium oxalate (KOx). The other four dogs were assigned to a control group and were injected intravenously with 0.9% NaCl three times a day (tid) for 7 consecutive days. Then kidneys were harvested for pathological, immunohistochemical examination and OPN and THP mRNA expression levels were quantified by quantitative real-time PCR.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 8%
Unknown 12 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 2 15%
Student > Master 2 15%
Lecturer 1 8%
Student > Bachelor 1 8%
Other 1 8%
Other 4 31%
Unknown 2 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 3 23%
Medicine and Dentistry 2 15%
Nursing and Health Professions 1 8%
Veterinary Science and Veterinary Medicine 1 8%
Physics and Astronomy 1 8%
Other 1 8%
Unknown 4 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2021.
All research outputs
#13,911,941
of 22,749,166 outputs
Outputs from BMC Veterinary Research
#1,017
of 3,039 outputs
Outputs of similar age
#126,569
of 243,429 outputs
Outputs of similar age from BMC Veterinary Research
#11
of 28 outputs
Altmetric has tracked 22,749,166 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,039 research outputs from this source. They receive a mean Attention Score of 3.8. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,429 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.