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Impact of body size, nutrition and socioeconomic position in early life on the epigenome: a systematic review protocol

Overview of attention for article published in Systematic Reviews, July 2017
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Title
Impact of body size, nutrition and socioeconomic position in early life on the epigenome: a systematic review protocol
Published in
Systematic Reviews, July 2017
DOI 10.1186/s13643-017-0521-8
Pubmed ID
Authors

Jane Maddock, Wahyu Wulaningsih, Rebecca Hardy

Abstract

Body size, nutrition and socioeconomic position (SEP) in early life have been associated with a range of later life health outcomes. Epigenetic regulation is one mechanism through which these early life factors may impact later life health. The aim of this review protocol is to outline procedures to document the influence of body size, nutrition and SEP in early life on the epigenome. MEDLINE, Embase and BIOSIS will be systematically searched using pre-defined keywords. Additional studies will be identified through manual searching of reference lists. Two independent researchers will assess the eligibility and quality of each study, with disagreements being resolved through discussion or a third reviewer. Studies will be included if they have epigenetic markers measured either at the same time as, or after, the early life exposure and, have a measure of body size, nutrition or SEP in early life (up to 12 years), are in the English language and are from a sample of community-dwelling participants. This protocol will be used to collate the evidence for the effect of early life factors on the epigenome. Findings will form a component of a wider research study examining epigenetic responses to exposures in early life and over the life course and its impact on healthy ageing using data from population-based cohort studies. PROSPERO CRD42016050193.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 22%
Student > Ph. D. Student 3 17%
Student > Bachelor 2 11%
Student > Doctoral Student 2 11%
Student > Master 1 6%
Other 0 0%
Unknown 6 33%
Readers by discipline Count As %
Medicine and Dentistry 4 22%
Social Sciences 2 11%
Biochemistry, Genetics and Molecular Biology 1 6%
Economics, Econometrics and Finance 1 6%
Psychology 1 6%
Other 2 11%
Unknown 7 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 July 2017.
All research outputs
#20,436,330
of 22,990,068 outputs
Outputs from Systematic Reviews
#1,920
of 2,005 outputs
Outputs of similar age
#273,185
of 313,314 outputs
Outputs of similar age from Systematic Reviews
#48
of 51 outputs
Altmetric has tracked 22,990,068 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,005 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.