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Anticancer activity of cationic porphyrins in melanoma tumour-bearing mice and mechanistic in vitro studies

Overview of attention for article published in Molecular Cancer, April 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

Mentioned by

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3 X users
patent
1 patent

Citations

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72 Dimensions

Readers on

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91 Mendeley
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Title
Anticancer activity of cationic porphyrins in melanoma tumour-bearing mice and mechanistic in vitro studies
Published in
Molecular Cancer, April 2014
DOI 10.1186/1476-4598-13-75
Pubmed ID
Authors

Valentina Rapozzi, Sonia Zorzet, Marina Zacchigna, Emilia Della Pietra, Susanna Cogoi, Luigi E Xodo

Abstract

Porphyrin TMPyP4 (P4) and its C14H28-alkyl derivative (C14) are G-quadruplex binders and singlet oxygen (1O2) generators. In contrast, TMPyP2 (P2) produces 1O2 but it is not a G-quadruplex binder. As their photosensitizing activity is currently undefined, we report in this study their efficacy against a melanoma skin tumour and describe an in vitro mechanistic study which gives insights into their anticancer activity.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
South Africa 1 1%
Unknown 90 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 18%
Student > Master 14 15%
Student > Bachelor 9 10%
Researcher 8 9%
Student > Doctoral Student 6 7%
Other 16 18%
Unknown 22 24%
Readers by discipline Count As %
Chemistry 19 21%
Agricultural and Biological Sciences 17 19%
Biochemistry, Genetics and Molecular Biology 13 14%
Pharmacology, Toxicology and Pharmaceutical Science 4 4%
Medicine and Dentistry 4 4%
Other 12 13%
Unknown 22 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2020.
All research outputs
#6,133,719
of 22,751,628 outputs
Outputs from Molecular Cancer
#415
of 1,717 outputs
Outputs of similar age
#58,451
of 226,111 outputs
Outputs of similar age from Molecular Cancer
#8
of 44 outputs
Altmetric has tracked 22,751,628 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 1,717 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,111 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.