Title |
Prevalence, predictors and outcome of hypofibrinogenaemia in trauma: a multicentre observational study
|
---|---|
Published in |
Critical Care, March 2014
|
DOI | 10.1186/cc13798 |
Pubmed ID | |
Authors |
Jostein S Hagemo, Simon Stanworth, Nicole P Juffermans, Karim Brohi, Mitchell Jay Cohen, Pär I Johansson, Jo Røislien, Torsten Eken, Paal A Næss, Christine Gaarder |
Abstract |
Exsanguination due to trauma-induced coagulopathy is a continuing challenge in emergency trauma care. Fibrinogen is a crucial factor for haemostatic competence, and may be the factor that reaches critically low levels first. Early fibrinogen substitution is advocated by a number of authors. Little evidence exists regarding the indications for fibrinogen supplementation in the acute phase. This study aims to estimate the prevalence of hypofibrinogenaemia in a multi-center trauma population, and to explore how initial fibrinogen concentration relates to outcome. Also, factors contributing to low fibrinogen levels are identified. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Sweden | 2 | 33% |
Norway | 1 | 17% |
United States | 1 | 17% |
United Kingdom | 1 | 17% |
Unknown | 1 | 17% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 50% |
Practitioners (doctors, other healthcare professionals) | 2 | 33% |
Science communicators (journalists, bloggers, editors) | 1 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 1 | <1% |
Canada | 1 | <1% |
Unknown | 102 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 19 | 18% |
Other | 16 | 15% |
Researcher | 12 | 12% |
Student > Postgraduate | 11 | 11% |
Student > Ph. D. Student | 11 | 11% |
Other | 20 | 19% |
Unknown | 15 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 70 | 67% |
Veterinary Science and Veterinary Medicine | 3 | 3% |
Agricultural and Biological Sciences | 3 | 3% |
Nursing and Health Professions | 3 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
Other | 7 | 7% |
Unknown | 16 | 15% |