Title |
PDA: Pooled DNA analyzer
|
---|---|
Published in |
BMC Bioinformatics, April 2006
|
DOI | 10.1186/1471-2105-7-233 |
Pubmed ID | |
Authors |
Hsin-Chou Yang, Chia-Ching Pan, Chin-Yu Lin, Cathy SJ Fann |
Abstract |
Association mapping using abundant single nucleotide polymorphisms is a powerful tool for identifying disease susceptibility genes for complex traits and exploring possible genetic diversity. Genotyping large numbers of SNPs individually is performed routinely but is cost prohibitive for large-scale genetic studies. DNA pooling is a reliable and cost-saving alternative genotyping method. However, no software has been developed for complete pooled-DNA analyses, including data standardization, allele frequency estimation, and single/multipoint DNA pooling association tests. This motivated the development of the software, 'PDA' (Pooled DNA Analyzer), to analyze pooled DNA data. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 10% |
Germany | 1 | 3% |
Australia | 1 | 3% |
Unknown | 33 | 85% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 12 | 31% |
Professor > Associate Professor | 8 | 21% |
Student > Ph. D. Student | 8 | 21% |
Professor | 3 | 8% |
Student > Doctoral Student | 2 | 5% |
Other | 3 | 8% |
Unknown | 3 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 19 | 49% |
Medicine and Dentistry | 9 | 23% |
Mathematics | 2 | 5% |
Engineering | 2 | 5% |
Earth and Planetary Sciences | 1 | 3% |
Other | 2 | 5% |
Unknown | 4 | 10% |