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Divergent effects of muscarinic receptor subtype gene ablation on murine colon tumorigenesis reveals association of M3R and zinc finger protein 277 expression in colon neoplasia

Overview of attention for article published in Molecular Cancer, April 2014
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Title
Divergent effects of muscarinic receptor subtype gene ablation on murine colon tumorigenesis reveals association of M3R and zinc finger protein 277 expression in colon neoplasia
Published in
Molecular Cancer, April 2014
DOI 10.1186/1476-4598-13-77
Pubmed ID
Authors

Kunrong Cheng, Guofeng Xie, Sandeep Khurana, Jonathon Heath, Cinthia B Drachenberg, Jennifer Timmons, Nirish Shah, Jean-Pierre Raufman

Abstract

M3 and M1 subtype muscarinic receptors are co-expressed in normal and neoplastic intestinal epithelial cells. In mice, ablating Chrm3, the gene encoding M3R, robustly attenuates intestinal tumor formation. Here we investigated the effects of Chrm1 gene ablation, alone and in combination with Chrm3 ablation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 17%
Student > Bachelor 3 13%
Student > Ph. D. Student 3 13%
Student > Master 3 13%
Professor > Associate Professor 2 9%
Other 3 13%
Unknown 5 22%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 22%
Medicine and Dentistry 3 13%
Pharmacology, Toxicology and Pharmaceutical Science 2 9%
Nursing and Health Professions 2 9%
Neuroscience 2 9%
Other 2 9%
Unknown 7 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 April 2014.
All research outputs
#15,298,293
of 22,751,628 outputs
Outputs from Molecular Cancer
#1,041
of 1,717 outputs
Outputs of similar age
#132,632
of 225,518 outputs
Outputs of similar age from Molecular Cancer
#26
of 45 outputs
Altmetric has tracked 22,751,628 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,717 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 225,518 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.