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Mendeley readers
| Title |
Plasmodium falciparum UvrD activities are downregulated by DNA-interacting compounds and its dsRNA inhibits malaria parasite growth
|
|---|---|
| Published in |
BMC Molecular and Cell Biology, April 2014
|
| DOI | 10.1186/1471-2091-15-9 |
| Pubmed ID | |
| Authors |
Mohammed Tarique, Farha Tabassum, Moaz Ahmad, Renu Tuteja, Malaria Group |
| Abstract |
Human malaria parasite infection and its control is a global challenge which is responsible for ~0.65 million deaths every year globally. The emergence of drug resistant malaria parasite is another challenge to fight with malaria. Enormous efforts are being made to identify suitable drug targets in order to develop newer classes of drug. Helicases play crucial roles in DNA metabolism and have been proposed as therapeutic targets for cancer therapy as well as viral and parasitic infections. Genome wide analysis revealed that Plasmodium falciparum possesses UvrD helicase, which is absent in the human host. |
Mendeley readers
The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 6% |
| Unknown | 17 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 3 | 17% |
| Researcher | 3 | 17% |
| Student > Ph. D. Student | 3 | 17% |
| Professor > Associate Professor | 2 | 11% |
| Student > Doctoral Student | 1 | 6% |
| Other | 3 | 17% |
| Unknown | 3 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 6 | 33% |
| Biochemistry, Genetics and Molecular Biology | 4 | 22% |
| Medicine and Dentistry | 2 | 11% |
| Immunology and Microbiology | 2 | 11% |
| Computer Science | 1 | 6% |
| Other | 0 | 0% |
| Unknown | 3 | 17% |