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Diverse viral glycoproteins as well as CD4 co-package into the same human immunodeficiency virus (HIV-1) particles

Overview of attention for article published in Retrovirology, April 2014
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Title
Diverse viral glycoproteins as well as CD4 co-package into the same human immunodeficiency virus (HIV-1) particles
Published in
Retrovirology, April 2014
DOI 10.1186/1742-4690-11-28
Pubmed ID
Authors

Devon A Gregory, Grace Y Olinger, Tiffany M Lucas, Marc C Johnson

Abstract

Retroviruses can acquire not only their own glycoproteins as they bud from the cellular membrane, but also some cellular and foreign viral glycoproteins. Many of these non-native glycoproteins are actively recruited to budding virions, particularly other viral glycoproteins. This observation suggests that there may be a conserved mechanism underlying the recruitment of glycoproteins into viruses. If a conserved mechanism is used, diverse glycoproteins should localize to a single budding retroviral particle. On the other hand, if viral glycoproteins have divergent mechanisms for recruitment, the different glycoproteins could segregate into different particles.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Netherlands 1 2%
Unknown 41 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 16%
Student > Bachelor 6 14%
Librarian 5 12%
Professor 5 12%
Student > Master 5 12%
Other 11 26%
Unknown 4 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 21%
Medicine and Dentistry 8 19%
Nursing and Health Professions 4 9%
Biochemistry, Genetics and Molecular Biology 4 9%
Immunology and Microbiology 4 9%
Other 9 21%
Unknown 5 12%