Title |
Diverse viral glycoproteins as well as CD4 co-package into the same human immunodeficiency virus (HIV-1) particles
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Published in |
Retrovirology, April 2014
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DOI | 10.1186/1742-4690-11-28 |
Pubmed ID | |
Authors |
Devon A Gregory, Grace Y Olinger, Tiffany M Lucas, Marc C Johnson |
Abstract |
Retroviruses can acquire not only their own glycoproteins as they bud from the cellular membrane, but also some cellular and foreign viral glycoproteins. Many of these non-native glycoproteins are actively recruited to budding virions, particularly other viral glycoproteins. This observation suggests that there may be a conserved mechanism underlying the recruitment of glycoproteins into viruses. If a conserved mechanism is used, diverse glycoproteins should localize to a single budding retroviral particle. On the other hand, if viral glycoproteins have divergent mechanisms for recruitment, the different glycoproteins could segregate into different particles. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
Netherlands | 1 | 2% |
Unknown | 41 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 16% |
Student > Bachelor | 6 | 14% |
Librarian | 5 | 12% |
Professor | 5 | 12% |
Student > Master | 5 | 12% |
Other | 11 | 26% |
Unknown | 4 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 9 | 21% |
Medicine and Dentistry | 8 | 19% |
Nursing and Health Professions | 4 | 9% |
Biochemistry, Genetics and Molecular Biology | 4 | 9% |
Immunology and Microbiology | 4 | 9% |
Other | 9 | 21% |
Unknown | 5 | 12% |